FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1607171391> ?p ?o ?g. }

• W1607171391 endingPage "44" @default.
• W1607171391 startingPage "438" @default.
• W1607171391 abstract "To assess the association of the use of domperidone in infants with QTc interval prolongation and proarrhythmic events.A systematic search of the scientific literature was conducted without any date or language restriction. The electronic database MEDLINE and the sources LILACS, ScIELO and Cochrane library were consulted.From the twelve identified studies, eight were excluded because they did not meet the inclusion criteria. One case report and three pilot studies were selected. Rocha et al (2005) reported the case of an infant (age 3 months) with QTc interval = 463 ms after being treated during one month with 1.8 mg/kg/day of oral domperidone. Djeddi et al (2008) administered an average dose of 1.3 mg/kg/day to 31 neonates; QTc interval prolongation > 30 ms was observed in nine neonates. Hegar et al (2009) studied 10 infants (mean age 5.6 months) who received 0.8 mg/ kg/day of oral domperidone; QTc interval prolongation was not observed. Günlemez et al (2010) enrolled 40 premature infants who were administered 1 mg/kg/day of oral domperidone; the QTc interval increased to above 450 ms in two infants.Although evidence that orally administrated domperidone in infants produces prolongation of QTc interval was found, further studies are needed in order to quantify the risk associated with the drug in that population. We suggest that heath professionals should conduct ECGs to infants treated with domperidone and inform the pharmacovigilance system the occurrence of any case of adverse event.Determinar si existe evidencia de prolongación del intervalo QTc y efectos proarrítmicos asociados al uso de domperidona oral en infantes.Se realizó una revisión sistemática de la literatura científica consultando la base de datos electrónica MEDLINE y las fuentes LILACS, ScIELO y Biblioteca Cochrane a través de la Biblioteca Virtual de Salud, sin límite de fecha ni de idioma.De los estudios identificados se excluyeron ocho por no cumplir con los criterios de inclusión, quedando seleccionados un reporte de caso y tres estudios pilotos. Rocha et al (2005) reportan el caso de un niño de 3 meses con intervalo QTc=463 mseg tras un mes de tratamiento con 1,8 mg/kg/día de domperidona oral. Djeddi et al (2008) administraron una dosis promedio de 1,3 mg/kg/día a 31 neonatos, observando prolongación del intervalo QTc>30 mseg en nueve. Hegar et al (2009) estudiaron a 10 niños con edad media de 5,6 meses tratados con 0,8 mg/kg/día y no observaron prolongación del intervalo QTc. Gunlemez et al (2010) incluyeron en su estudio a 40 infantes prematuros a quienes administraron 1 mg/kg/día de domperidona oral, en dos de ellos el intervalo QTc aumentó por encima de 450 mseg.Aunque se encontró evidencia de prolongación del intervalo QTc en infantes tratados con domperidona oral, se necesitan más estudios para cuantificar el riesgo asociado a la droga en esta población. Se sugiere a los profesionales de la salud realizar un monitoreo electrocardiográfico de los infantes tratados con domperidona e informar al sistema de farmacovigilancia los casos de ocurrencia de eventos adversos." @default.
• W1607171391 created "2016-06-24" @default.
• W1607171391 creator A5009616752 @default.
• W1607171391 creator A5061462966 @default.
• W1607171391 creator A5069159743 @default.
• W1607171391 creator A5080041044 @default.
• W1607171391 creator A5082624829 @default.
• W1607171391 creator A5086257127 @default.
• W1607171391 date "2014-09-16" @default.
• W1607171391 modified "2023-09-23" @default.
• W1607171391 title "[Proarrhythmic effects of domperidone in infants: a systematic review]." @default.
• W1607171391 cites W1373987 @default.
• W1607171391 cites W1590032415 @default.
• W1607171391 cites W1966258408 @default.
• W1607171391 cites W1970509752 @default.
• W1607171391 cites W1971880486 @default.
• W1607171391 cites W1982182190 @default.
• W1607171391 cites W2014213574 @default.
• W1607171391 cites W2022774950 @default.
• W1607171391 cites W2031153645 @default.
• W1607171391 cites W2039434484 @default.
• W1607171391 cites W2040475006 @default.
• W1607171391 cites W2049902803 @default.
• W1607171391 cites W2107619722 @default.
• W1607171391 cites W2138784551 @default.
• W1607171391 cites W2172237983 @default.
• W1607171391 cites W2211090943 @default.
• W1607171391 cites W2277784299 @default.
• W1607171391 cites W2338650238 @default.
• W1607171391 cites W3013515259 @default.
• W1607171391 doi "https://doi.org/10.7399/fh.2014.38.5.7957" @default.
• W1607171391 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25344138" @default.
• W1607171391 hasPublicationYear "2014" @default.
• W1607171391 type Work @default.
• W1607171391 sameAs 1607171391 @default.
• W1607171391 citedByCount "2" @default.
• W1607171391 countsByYear W16071713912019 @default.
• W1607171391 countsByYear W16071713912021 @default.
• W1607171391 crossrefType "journal-article" @default.
• W1607171391 hasAuthorship W1607171391A5009616752 @default.
• W1607171391 hasAuthorship W1607171391A5061462966 @default.
• W1607171391 hasAuthorship W1607171391A5069159743 @default.
• W1607171391 hasAuthorship W1607171391A5080041044 @default.
• W1607171391 hasAuthorship W1607171391A5082624829 @default.
• W1607171391 hasAuthorship W1607171391A5086257127 @default.
• W1607171391 hasConcept C118441451 @default.
• W1607171391 hasConcept C126322002 @default.
• W1607171391 hasConcept C187212893 @default.
• W1607171391 hasConcept C197934379 @default.
• W1607171391 hasConcept C2775995038 @default.
• W1607171391 hasConcept C2776478404 @default.
• W1607171391 hasConcept C2908647359 @default.
• W1607171391 hasConcept C42219234 @default.
• W1607171391 hasConcept C44249647 @default.
• W1607171391 hasConcept C513476851 @default.
• W1607171391 hasConcept C57658597 @default.
• W1607171391 hasConcept C71924100 @default.
• W1607171391 hasConcept C99454951 @default.
• W1607171391 hasConceptScore W1607171391C118441451 @default.
• W1607171391 hasConceptScore W1607171391C126322002 @default.
• W1607171391 hasConceptScore W1607171391C187212893 @default.
• W1607171391 hasConceptScore W1607171391C197934379 @default.
• W1607171391 hasConceptScore W1607171391C2775995038 @default.
• W1607171391 hasConceptScore W1607171391C2776478404 @default.
• W1607171391 hasConceptScore W1607171391C2908647359 @default.
• W1607171391 hasConceptScore W1607171391C42219234 @default.
• W1607171391 hasConceptScore W1607171391C44249647 @default.
• W1607171391 hasConceptScore W1607171391C513476851 @default.
• W1607171391 hasConceptScore W1607171391C57658597 @default.
• W1607171391 hasConceptScore W1607171391C71924100 @default.
• W1607171391 hasConceptScore W1607171391C99454951 @default.
• W1607171391 hasIssue "5" @default.
• W1607171391 hasLocation W16071713911 @default.
• W1607171391 hasOpenAccess W1607171391 @default.
• W1607171391 hasPrimaryLocation W16071713911 @default.
• W1607171391 hasRelatedWork W2019086812 @default.
• W1607171391 hasRelatedWork W2056693918 @default.
• W1607171391 hasRelatedWork W2110954332 @default.
• W1607171391 hasRelatedWork W2899084033 @default.
• W1607171391 hasRelatedWork W2917524362 @default.
• W1607171391 hasRelatedWork W3030434109 @default.
• W1607171391 hasRelatedWork W3126282393 @default.
• W1607171391 hasRelatedWork W3148728405 @default.
• W1607171391 hasRelatedWork W4232581825 @default.
• W1607171391 hasRelatedWork W4281254660 @default.
• W1607171391 hasVolume "38" @default.
• W1607171391 isParatext "false" @default.
• W1607171391 isRetracted "false" @default.
• W1607171391 magId "1607171391" @default.
• W1607171391 workType "article" @default.