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• W1607314963 abstract "1.1 From lesions to functional neuroimaging The first model about the cerebral organization of cognitive functions was based on lesion observation. This consisted in inferring association between a particular deficit of the language (e.g., word production) and a brain lesion observed post-mortem (Wernicke, 1874; Broca, 1861). Brain imaging techniques (e.g., functional Magnetic Resonance Imaging) provide complementary but different types of information regarding brain-behavior relationships. By providing indirect measures of cerebral activity such as blood flow or oxygen consumption, neuroimaging techniques enable one to establish a relationship between the activities of different brain areas and the cognitive processes being performed (Bestmann et al. 2003; Frith 1997). For instance, the combination of functional magnetic resonance imaging (fMRI) with language tasks has shown that language-related areas have a more complex role than the ones attributed by lesion studies, e.g. Broca’s area in the left inferior frontal gyrus has been involved in speech production as well as in speech comprehension, and Wernicke’s area located in the left temporoparietal area has been involved in language comprehension as well as phoneme discrimination (Friederici 2002; Luke et al. 2002). In addition, brain imaging studies showed that language processing is not restricted to Broca’s and Wernicke’s areas as shown by lesion studies, but requires a network of different brain areas which may be interconnected (Catani, Jones, and ffytche 2005; Behrens et al. 2003). However, the measures of brain activity implicate rather than demonstrate the critical contribution of a brain area to behavior, which can lead to misinterpretations." @default.
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• W1607314963 date "2012-02-17" @default.
• W1607314963 modified "2023-09-23" @default.
• W1607314963 title "A Triangulation-Based MRI-Guided Method for TMS Coil Positioning" @default.
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• W1607314963 doi "https://doi.org/10.5772/23910" @default.
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