Matches in SemOpenAlex for { <https://semopenalex.org/work/W1607452187> ?p ?o ?g. }
- W1607452187 endingPage "188" @default.
- W1607452187 startingPage "180" @default.
- W1607452187 abstract "Aim To examine the relationship between cardiorespiratory fitness ( CRF ) and risk of incident heart failure ( HF ). Methods and results Cardiorespiratory fitness, as measured by maximal oxygen uptake ( VO 2 max ), was assessed at baseline in a prospective cohort of 1873 men aged 42–61 years without HF or chronic respiratory disease. During a mean follow‐up of 20.4 years, 152 incident HF events were recorded. Within‐person variability was calculated using data from repeat measurements taken 11 years apart. The age‐adjusted hazard ratio ( HR ) per unit increase (1 mL /kg/min of VO 2 max ) in CRF was 0.89 [95% confidence interval ( CI ) 0.86–0.93], which was minimally attenuated to 0.94 (95% CI 0.90–0.98) after further adjustment for established HF risk factors (body mass index, systolic blood pressure, history of cardiovascular disease, diabetes, heart rate, and LV hypertrophy) and incident coronary events as a time‐varying covariate. In a comparison of extreme quartiles of CRF levels ( VO 2 max ≥35.4 vs. ≤25.7 mL /kg/min), the corresponding HRs were 0.27 (0.15–0.50) and 0.48 (0.25–0.92), respectively. Each 1 MET (metabolic equivalent of oxygen consumption) increment in CRF was associated with a 21% (7–33%) reduction in multivariable adjusted risk of HF . Addition of CRF to a HF risk prediction model containing established risk factors did not significantly improve risk discrimination (C‐index change = 0.0164, P = 0.07). Conclusions In this Finnish population, there is a strong, inverse, and independent association between long‐term CRF and HF risk, consistent with a dose–response relationship. The protective effect of CRF on HF risk warrants further evaluation." @default.
- W1607452187 created "2016-06-24" @default.
- W1607452187 creator A5006008613 @default.
- W1607452187 creator A5014232823 @default.
- W1607452187 creator A5022314919 @default.
- W1607452187 creator A5024248101 @default.
- W1607452187 creator A5024302828 @default.
- W1607452187 creator A5053917493 @default.
- W1607452187 creator A5070151669 @default.
- W1607452187 creator A5086547393 @default.
- W1607452187 date "2013-12-14" @default.
- W1607452187 modified "2023-10-17" @default.
- W1607452187 title "Cardiorespiratory fitness and risk of heart failure: a population‐based follow‐up study" @default.
- W1607452187 cites W1945012547 @default.
- W1607452187 cites W1971474283 @default.
- W1607452187 cites W1975659314 @default.
- W1607452187 cites W1980702134 @default.
- W1607452187 cites W1981369237 @default.
- W1607452187 cites W1989687645 @default.
- W1607452187 cites W2017390118 @default.
- W1607452187 cites W2023914545 @default.
- W1607452187 cites W2031791006 @default.
- W1607452187 cites W2033655946 @default.
- W1607452187 cites W2036797203 @default.
- W1607452187 cites W2036883509 @default.
- W1607452187 cites W2045113865 @default.
- W1607452187 cites W2045798430 @default.
- W1607452187 cites W2055350029 @default.
- W1607452187 cites W2066187800 @default.
- W1607452187 cites W2080208389 @default.
- W1607452187 cites W2085122671 @default.
- W1607452187 cites W2092807552 @default.
- W1607452187 cites W2103394333 @default.
- W1607452187 cites W2103965307 @default.
- W1607452187 cites W2106421416 @default.
- W1607452187 cites W2109348687 @default.
- W1607452187 cites W2112316706 @default.
- W1607452187 cites W2116192143 @default.
- W1607452187 cites W2123279057 @default.
- W1607452187 cites W2129925362 @default.
- W1607452187 cites W2139219244 @default.
- W1607452187 cites W2140020246 @default.
- W1607452187 cites W2144359368 @default.
- W1607452187 cites W2145681479 @default.
- W1607452187 cites W2160117042 @default.
- W1607452187 cites W2165003047 @default.
- W1607452187 cites W2170785660 @default.
- W1607452187 cites W2320228217 @default.
- W1607452187 cites W2326400675 @default.
- W1607452187 cites W2326572543 @default.
- W1607452187 cites W2328965873 @default.
- W1607452187 cites W2332619349 @default.
- W1607452187 cites W2332951586 @default.
- W1607452187 cites W2338226229 @default.
- W1607452187 cites W2470285974 @default.
- W1607452187 cites W3165153188 @default.
- W1607452187 cites W4212824063 @default.
- W1607452187 cites W4232464268 @default.
- W1607452187 cites W4250014314 @default.
- W1607452187 cites W4320300836 @default.
- W1607452187 doi "https://doi.org/10.1111/ejhf.37" @default.
- W1607452187 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24464981" @default.
- W1607452187 hasPublicationYear "2013" @default.
- W1607452187 type Work @default.
- W1607452187 sameAs 1607452187 @default.
- W1607452187 citedByCount "97" @default.
- W1607452187 countsByYear W16074521872015 @default.
- W1607452187 countsByYear W16074521872016 @default.
- W1607452187 countsByYear W16074521872017 @default.
- W1607452187 countsByYear W16074521872018 @default.
- W1607452187 countsByYear W16074521872019 @default.
- W1607452187 countsByYear W16074521872020 @default.
- W1607452187 countsByYear W16074521872021 @default.
- W1607452187 countsByYear W16074521872022 @default.
- W1607452187 countsByYear W16074521872023 @default.
- W1607452187 crossrefType "journal-article" @default.
- W1607452187 hasAuthorship W1607452187A5006008613 @default.
- W1607452187 hasAuthorship W1607452187A5014232823 @default.
- W1607452187 hasAuthorship W1607452187A5022314919 @default.
- W1607452187 hasAuthorship W1607452187A5024248101 @default.
- W1607452187 hasAuthorship W1607452187A5024302828 @default.
- W1607452187 hasAuthorship W1607452187A5053917493 @default.
- W1607452187 hasAuthorship W1607452187A5070151669 @default.
- W1607452187 hasAuthorship W1607452187A5086547393 @default.
- W1607452187 hasBestOaLocation W16074521871 @default.
- W1607452187 hasConcept C117437137 @default.
- W1607452187 hasConcept C126322002 @default.
- W1607452187 hasConcept C134018914 @default.
- W1607452187 hasConcept C164705383 @default.
- W1607452187 hasConcept C188816634 @default.
- W1607452187 hasConcept C196310339 @default.
- W1607452187 hasConcept C207103383 @default.
- W1607452187 hasConcept C2777953023 @default.
- W1607452187 hasConcept C2778198053 @default.
- W1607452187 hasConcept C2780221984 @default.
- W1607452187 hasConcept C2908647359 @default.
- W1607452187 hasConcept C44249647 @default.
- W1607452187 hasConcept C50382708 @default.