FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1607664237> ?p ?o ?g. }

• W1607664237 endingPage "744" @default.
• W1607664237 startingPage "735" @default.
• W1607664237 abstract "Treatment with ouabain led to massive death of principal cells from collecting ducts (C7-MDCK), indicated by cell swelling, loss of mitochondrial function, an irregular pattern of DNA degradation, and insensitivity to pan-caspase inhibitor. Equimolar substitution of extracellular Na(+) by K(+) or choline(+) sharply attenuated the effect of ouabain on intracellular Na(+) and K(+) content but did not protect the cells from death in the presence of ouabain. In contrast to ouabain, inhibition of the Na(+)/K(+) pump in K(+)-free medium increased Na(+)(i) content but did not affect cell survival. In control and K(+)-free medium, ouabain triggered half-maximal cell death at concentrations of approximately 0.5 and 0.05 microM, respectively, which was consistent with elevation of Na(+)/K(+) pump sensitivity to ouabain in K(+)-depleted medium. Our results show for the first time that the death of ouabain-treated renal epithelial cells is independent of the inhibition of Na(+)/K(+) pump-mediated ion fluxes and the [Na(+)](i)]/[K(+)](i) ratio." @default.
• W1607664237 created "2016-06-24" @default.
• W1607664237 creator A5014784161 @default.
• W1607664237 creator A5025314043 @default.
• W1607664237 creator A5025572908 @default.
• W1607664237 creator A5031351161 @default.
• W1607664237 creator A5036314502 @default.
• W1607664237 creator A5039985404 @default.
• W1607664237 creator A5059710002 @default.
• W1607664237 creator A5068046329 @default.
• W1607664237 creator A5078542746 @default.
• W1607664237 date "2003-02-01" @default.
• W1607664237 modified "2023-10-01" @default.
• W1607664237 title "Inhibition of Na+,K+-ATPase by ouabain triggers epithelial cell death independently of inversion of the [Na+]i/[K+]i ratio" @default.
• W1607664237 cites W1545964478 @default.
• W1607664237 cites W1684019827 @default.
• W1607664237 cites W181484884 @default.
• W1607664237 cites W1964171092 @default.
• W1607664237 cites W1967394868 @default.
• W1607664237 cites W1968320638 @default.
• W1607664237 cites W1969800959 @default.
• W1607664237 cites W1970626930 @default.
• W1607664237 cites W1971939539 @default.
• W1607664237 cites W1986024151 @default.
• W1607664237 cites W1987401644 @default.
• W1607664237 cites W1988071723 @default.
• W1607664237 cites W1988201508 @default.
• W1607664237 cites W1990053315 @default.
• W1607664237 cites W1991870376 @default.
• W1607664237 cites W1993509170 @default.
• W1607664237 cites W1993959003 @default.
• W1607664237 cites W1996265796 @default.
• W1607664237 cites W1998033241 @default.
• W1607664237 cites W2007939817 @default.
• W1607664237 cites W2010587120 @default.
• W1607664237 cites W2028493848 @default.
• W1607664237 cites W2033844831 @default.
• W1607664237 cites W2035325191 @default.
• W1607664237 cites W2036850744 @default.
• W1607664237 cites W2044503856 @default.
• W1607664237 cites W2065314664 @default.
• W1607664237 cites W2070908828 @default.
• W1607664237 cites W2077465227 @default.
• W1607664237 cites W2082786285 @default.
• W1607664237 cites W2097814316 @default.
• W1607664237 cites W2109193104 @default.
• W1607664237 cites W2110225954 @default.
• W1607664237 cites W2114918609 @default.
• W1607664237 cites W2115638394 @default.
• W1607664237 cites W2116947619 @default.
• W1607664237 cites W2127179996 @default.
• W1607664237 cites W2130400575 @default.
• W1607664237 cites W2133349188 @default.
• W1607664237 cites W2144470409 @default.
• W1607664237 cites W2148999077 @default.
• W1607664237 cites W2162369109 @default.
• W1607664237 cites W2220784010 @default.
• W1607664237 cites W2248934156 @default.
• W1607664237 cites W2335815721 @default.
• W1607664237 cites W2338021565 @default.
• W1607664237 cites W2346528545 @default.
• W1607664237 cites W2417547090 @default.
• W1607664237 cites W76529961 @default.
• W1607664237 doi "https://doi.org/10.1016/s0006-291x(02)03002-4" @default.
• W1607664237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12565842" @default.
• W1607664237 hasPublicationYear "2003" @default.
• W1607664237 type Work @default.
• W1607664237 sameAs 1607664237 @default.
• W1607664237 citedByCount "66" @default.
• W1607664237 countsByYear W16076642372012 @default.
• W1607664237 countsByYear W16076642372013 @default.
• W1607664237 countsByYear W16076642372014 @default.
• W1607664237 countsByYear W16076642372015 @default.
• W1607664237 countsByYear W16076642372016 @default.
• W1607664237 countsByYear W16076642372017 @default.
• W1607664237 countsByYear W16076642372018 @default.
• W1607664237 countsByYear W16076642372020 @default.
• W1607664237 countsByYear W16076642372021 @default.
• W1607664237 crossrefType "journal-article" @default.
• W1607664237 hasAuthorship W1607664237A5014784161 @default.
• W1607664237 hasAuthorship W1607664237A5025314043 @default.
• W1607664237 hasAuthorship W1607664237A5025572908 @default.
• W1607664237 hasAuthorship W1607664237A5031351161 @default.
• W1607664237 hasAuthorship W1607664237A5036314502 @default.
• W1607664237 hasAuthorship W1607664237A5039985404 @default.
• W1607664237 hasAuthorship W1607664237A5059710002 @default.
• W1607664237 hasAuthorship W1607664237A5068046329 @default.
• W1607664237 hasAuthorship W1607664237A5078542746 @default.
• W1607664237 hasConcept C12554922 @default.
• W1607664237 hasConcept C126322002 @default.
• W1607664237 hasConcept C134018914 @default.
• W1607664237 hasConcept C153911025 @default.
• W1607664237 hasConcept C178790620 @default.
• W1607664237 hasConcept C185592680 @default.
• W1607664237 hasConcept C190283241 @default.
• W1607664237 hasConcept C2778375661 @default.
• W1607664237 hasConcept C2779133857 @default.
• W1607664237 hasConcept C2781123555 @default.

• next