Matches in SemOpenAlex for { <https://semopenalex.org/work/W1607811014> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1607811014 abstract "Being a part of Chinese as well as ayurdic herbal system, roots of Rumex hastatus D. Don (RH) is highly medicinal, used to regulated blood pressure. It is also reported that the plant is diuretic, laxative, tonic, used against microbial skin diseases, bilious complaints and jaundice. The present study is conducted to evaluate phytochemical, antimicrobial, antitumor and cytotoxic activities of extract obtained from R. hastatus roots.RH roots were powdered and extracted with methanol to get crude extract. Crude extract was further fractioned on the basis of increasing polarity, with n-hexane (HRR), chloroform (CRR), ethyl acetate (ERR), n-butanol (BRR) and residual aqueous fraction (ARR). Methanol extract and its derived fractions were subjected to phytochemical screening and assayed for antibacterial activities via agar well diffusion method. Antifungal activities were checked through agar tube dilution method whereas potato disc assay was employed for the determination of antitumor activity. On the other hand cytotoxic activities were conducted using brine shrimps procedures.The results obtained from phytochemical analysis indicate the presence of alkaloids, anthraquinones, flavonoids and saponins in all the fractions. Most of the plant fractions showed substantial antimicrobial activities, which is in accordance with the spacious use of tested plant samples in primary healthcare center. Fractions of R. hastatus roots for cytotoxicity were tested as an effective cytotoxic was found as BRR > MRR > CRR > ARR > ERR > HRR. Ranking order of fractions of R. hastatus roots for effective antitumor screening was found as MRR > BRR > ARR > CRR > ERR > HRR.These results showed that R. hastatus appeared as an important source for the discovery of new antimicrobial drugs and antitumor agents; verify its traditional uses and its exploitation as therapeutic agent." @default.
- W1607811014 created "2016-06-24" @default.
- W1607811014 creator A5025237492 @default.
- W1607811014 creator A5046868303 @default.
- W1607811014 creator A5063260328 @default.
- W1607811014 creator A5079551997 @default.
- W1607811014 date "2015-07-03" @default.
- W1607811014 modified "2023-10-14" @default.
- W1607811014 title "Evaluation of phytochemical content, antimicrobial, cytotoxic and antitumor activities of extract from Rumex hastatus D. Don roots" @default.
- W1607811014 cites W1515387645 @default.
- W1607811014 cites W1589912771 @default.
- W1607811014 cites W1993187699 @default.
- W1607811014 cites W2007887352 @default.
- W1607811014 cites W2011767614 @default.
- W1607811014 cites W2029423388 @default.
- W1607811014 cites W2037343199 @default.
- W1607811014 cites W2043337384 @default.
- W1607811014 cites W2074509460 @default.
- W1607811014 cites W2079292424 @default.
- W1607811014 cites W2081648574 @default.
- W1607811014 cites W2084588991 @default.
- W1607811014 cites W2093980210 @default.
- W1607811014 cites W2110837175 @default.
- W1607811014 cites W2153334914 @default.
- W1607811014 cites W2159097326 @default.
- W1607811014 cites W76991188 @default.
- W1607811014 doi "https://doi.org/10.1186/s12906-015-0736-y" @default.
- W1607811014 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4490637" @default.
- W1607811014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26138389" @default.
- W1607811014 hasPublicationYear "2015" @default.
- W1607811014 type Work @default.
- W1607811014 sameAs 1607811014 @default.
- W1607811014 citedByCount "17" @default.
- W1607811014 countsByYear W16078110142016 @default.
- W1607811014 countsByYear W16078110142017 @default.
- W1607811014 countsByYear W16078110142019 @default.
- W1607811014 countsByYear W16078110142020 @default.
- W1607811014 countsByYear W16078110142021 @default.
- W1607811014 countsByYear W16078110142022 @default.
- W1607811014 crossrefType "journal-article" @default.
- W1607811014 hasAuthorship W1607811014A5025237492 @default.
- W1607811014 hasAuthorship W1607811014A5046868303 @default.
- W1607811014 hasAuthorship W1607811014A5063260328 @default.
- W1607811014 hasAuthorship W1607811014A5079551997 @default.
- W1607811014 hasBestOaLocation W16078110141 @default.
- W1607811014 hasConcept C178790620 @default.
- W1607811014 hasConcept C185592680 @default.
- W1607811014 hasConcept C195475562 @default.
- W1607811014 hasConcept C2778660310 @default.
- W1607811014 hasConcept C2780104969 @default.
- W1607811014 hasConcept C2780867653 @default.
- W1607811014 hasConcept C4937899 @default.
- W1607811014 hasConcept C523546767 @default.
- W1607811014 hasConcept C54355233 @default.
- W1607811014 hasConcept C556039675 @default.
- W1607811014 hasConcept C59822182 @default.
- W1607811014 hasConcept C71924100 @default.
- W1607811014 hasConcept C86803240 @default.
- W1607811014 hasConceptScore W1607811014C178790620 @default.
- W1607811014 hasConceptScore W1607811014C185592680 @default.
- W1607811014 hasConceptScore W1607811014C195475562 @default.
- W1607811014 hasConceptScore W1607811014C2778660310 @default.
- W1607811014 hasConceptScore W1607811014C2780104969 @default.
- W1607811014 hasConceptScore W1607811014C2780867653 @default.
- W1607811014 hasConceptScore W1607811014C4937899 @default.
- W1607811014 hasConceptScore W1607811014C523546767 @default.
- W1607811014 hasConceptScore W1607811014C54355233 @default.
- W1607811014 hasConceptScore W1607811014C556039675 @default.
- W1607811014 hasConceptScore W1607811014C59822182 @default.
- W1607811014 hasConceptScore W1607811014C71924100 @default.
- W1607811014 hasConceptScore W1607811014C86803240 @default.
- W1607811014 hasIssue "1" @default.
- W1607811014 hasLocation W16078110141 @default.
- W1607811014 hasLocation W16078110142 @default.
- W1607811014 hasLocation W16078110143 @default.
- W1607811014 hasLocation W16078110144 @default.
- W1607811014 hasOpenAccess W1607811014 @default.
- W1607811014 hasPrimaryLocation W16078110141 @default.
- W1607811014 hasRelatedWork W1548904795 @default.
- W1607811014 hasRelatedWork W2062604169 @default.
- W1607811014 hasRelatedWork W2327181514 @default.
- W1607811014 hasRelatedWork W2397244892 @default.
- W1607811014 hasRelatedWork W2602254836 @default.
- W1607811014 hasRelatedWork W2752277825 @default.
- W1607811014 hasRelatedWork W2888596225 @default.
- W1607811014 hasRelatedWork W2893796386 @default.
- W1607811014 hasRelatedWork W3192815398 @default.
- W1607811014 hasRelatedWork W4285320868 @default.
- W1607811014 hasVolume "15" @default.
- W1607811014 isParatext "false" @default.
- W1607811014 isRetracted "false" @default.
- W1607811014 magId "1607811014" @default.
- W1607811014 workType "article" @default.