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- W1607956294 abstract "Objective To explore anaerobic dysbacteria associated with ulcerative colitis and the method of detection,look for effective Chinese medicine to treat ulcerative colitis.Method The ulcerative colitis rat's model was induced by glacial acetic acid and treated with Chinese medicine FuFang ShuShe(Compound Ganoderma lipsiense).The anaerobic bacteria and the content of volatile fatty acids were detected in each group during treatment.Common section and HE staining were used to observe pathological changes.Result(1) The content of volatile fatty acids in the model group was obviously lower than that of normal group(P0.05).The pH increased from the second day and was obviously higher than that of normal control group.The differences between the spontaneous recovery group and each treatment group were significant(P0.05).(2) There were difference in the score of inflammation between spontaneous recovery group and each treatment group(P0.01).The comparison between each treatment group showed the Chinese medicine plus Bifidobiogen-Livzon group had the lowest score of tissue damage(P0.05).Conclusion(1) Detection of the content of volatile fatty acids can be used in diagnosis of anaerobic dysbacteria.(2) Compound ShuShe can act as a prebiotic to adjust intestinal dysbacteria and repair mucosa,and is obviously effective on ulcerative colitis." @default.
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- W1607956294 date "2009-01-01" @default.
- W1607956294 modified "2023-09-24" @default.
- W1607956294 title "Diagnosis of dysbacteria in rats with ulcerative colitis and observation of treatment with compound ShuShe (Ganoderma lipsiense)." @default.
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