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• W1608259802 abstract "Objective: To determine the levels and ratios of serum LH, FSH and Testosterone, among men havinghistory of infertility.Material and Methods: A non-interventional descriptive study was carried out in the Department ofPublic Health Laboratories Division, NIH, Islamabad from January 2004 to December 2005. Two hundredfifty infertile men, classified as azoospermic (50), oligozoospermic (75), asthenozoospermic (50) andnormozoospermic (75) were studied for serum LH, FSH and Testosterone, in addition to 50 proven fathers.Results: The respective FSH (mIU/ml), LH (mIU/ml) and Testosterone (nmol/L) levels for the groups were22.924.15, 13.852.33 and 11.860.70 (Azoospermia), 16.823.79, 10.921.22 and 11.88+1.06(Oligozoospermia), 3.220.61, 3.921.17 and 16.24+2.05 (Asthenozoospermia) while in normozoospermicmen were 5.530.52, 7.400.60 and 17.29+1.02, The proven fathers group had 7.74+0.71 mIU/ml LH,6.75+1.06 mIU/ml FSH and 15.88+1.15 nmol/ml testosterone, respectively.The LH/FSH and FSH/LH ratios were 0.77+0.08 and 1.84+0.22 (Azoospermia), 1.78+0.41 and 1.47+0.18(Oligozoospermia), 1.51+0.46 and 1.28+0.28 (Asthenozoospermia) while in normozoospermic and provenfathers were 1.55+0.16 and 0.85+0.10,1.67+0.22 and0.94+0.12. Similarly, the LH/T and T/LH ratios were1.17+0.28 and 0.86+2.70 (Azoospermia), 0.92+0.28 and 1.08+0.17 (Oligozoospermia), 0.30+0.10 and4.14+10.4 (Asthenozoospermia) and in normozoospermic were 0.42+0.08 and 2.34+0.48.The ratiosobserved for T/FSH and FSH/T were 0.52+0.17 and 1.93+5.95 (Azoospermia), 0.71+0.28 and 1.42+3.57(Oligozoospermia), 5.04+3.38 and 0.20+0.30 (Asthenozoospermia) and in normozoospermic men were2.82+0.90 and 0.35+1.12, while in proven fathers were 4.09+0.57and 1.04+0.53 respectively.Conclusion: Altered/disturbed concentrations of gonadotropins and androgenic hormones and their ratioscause infertility, since all these hormones act synergistically." @default.
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• W1608259802 date "2007-01-01" @default.
• W1608259802 modified "2023-09-25" @default.
• W1608259802 title "DETERMINATION OF SERUM GONADOTROPIN AND TESTOSTERONE LEVELS IN MALE INFERTILITY" @default.
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