Matches in SemOpenAlex for { <https://semopenalex.org/work/W1608316354> ?p ?o ?g. }
- W1608316354 endingPage "3129" @default.
- W1608316354 startingPage "3119" @default.
- W1608316354 abstract "The ability of embryonic stem cells to develop into multiple cell lineages provides a powerful resource for tissue repair and regeneration. Gene transfer offers a means to dissect the complex events in lineage determination but is limited by current delivery systems. We designed a high-efficiency replication-defective herpes simplex virus gene transfer vector (JDbetabeta) for robust and transient expression of the transcription factors Pax3 and MyoD, which are known to be involved in skeletal muscle differentiation. JDbetabeta-mediated expression of each gene in day 4 embryoid bodies (early-stage mesoderm) resulted in the induction of unique alterations in gene expression profiles, including the upregulation of known target genes relevant to muscle and neural crest development, whereas a control enhanced green fluorescent protein expression vector was relatively inert. This vector delivery system holds great promise for the use of gene transfer to analyze the impact of specific genes on both regulatory genetic events and commitment of stem cells to particular lineages." @default.
- W1608316354 created "2016-06-24" @default.
- W1608316354 creator A5002037432 @default.
- W1608316354 creator A5009588472 @default.
- W1608316354 creator A5017226641 @default.
- W1608316354 creator A5031687021 @default.
- W1608316354 creator A5049641549 @default.
- W1608316354 creator A5058605320 @default.
- W1608316354 creator A5081723295 @default.
- W1608316354 date "2008-09-11" @default.
- W1608316354 modified "2023-09-30" @default.
- W1608316354 title "Herpes Simplex Virus-Mediated Expression of Pax3 and MyoD in Embryoid Bodies Results in Lineage-Related Alterations in Gene Expression Profiles" @default.
- W1608316354 cites W110925524 @default.
- W1608316354 cites W1503107508 @default.
- W1608316354 cites W1516008369 @default.
- W1608316354 cites W1555996845 @default.
- W1608316354 cites W1621865896 @default.
- W1608316354 cites W1670526549 @default.
- W1608316354 cites W1832267083 @default.
- W1608316354 cites W1968724600 @default.
- W1608316354 cites W1981021739 @default.
- W1608316354 cites W1983955010 @default.
- W1608316354 cites W1992924696 @default.
- W1608316354 cites W1995968204 @default.
- W1608316354 cites W1999064296 @default.
- W1608316354 cites W2003742149 @default.
- W1608316354 cites W2004196170 @default.
- W1608316354 cites W2004702539 @default.
- W1608316354 cites W2008901697 @default.
- W1608316354 cites W2010417854 @default.
- W1608316354 cites W2024843140 @default.
- W1608316354 cites W2025668858 @default.
- W1608316354 cites W2036314082 @default.
- W1608316354 cites W2045742275 @default.
- W1608316354 cites W2054403078 @default.
- W1608316354 cites W2054564420 @default.
- W1608316354 cites W2055932489 @default.
- W1608316354 cites W2065535087 @default.
- W1608316354 cites W2066121149 @default.
- W1608316354 cites W2070587104 @default.
- W1608316354 cites W2071496358 @default.
- W1608316354 cites W2077368081 @default.
- W1608316354 cites W2094478754 @default.
- W1608316354 cites W2104746754 @default.
- W1608316354 cites W2107277218 @default.
- W1608316354 cites W2114155063 @default.
- W1608316354 cites W2117544229 @default.
- W1608316354 cites W2120060713 @default.
- W1608316354 cites W2131738138 @default.
- W1608316354 cites W2135735391 @default.
- W1608316354 cites W2136164099 @default.
- W1608316354 cites W2139020188 @default.
- W1608316354 cites W2145224325 @default.
- W1608316354 cites W2146870828 @default.
- W1608316354 cites W2150712887 @default.
- W1608316354 cites W2159256388 @default.
- W1608316354 cites W2160503088 @default.
- W1608316354 cites W2161191369 @default.
- W1608316354 cites W2164235774 @default.
- W1608316354 cites W2166697185 @default.
- W1608316354 cites W2172252932 @default.
- W1608316354 cites W2173863177 @default.
- W1608316354 cites W2318207414 @default.
- W1608316354 cites W2330427748 @default.
- W1608316354 doi "https://doi.org/10.1634/stemcells.2008-0417" @default.
- W1608316354 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18787207" @default.
- W1608316354 hasPublicationYear "2008" @default.
- W1608316354 type Work @default.
- W1608316354 sameAs 1608316354 @default.
- W1608316354 citedByCount "13" @default.
- W1608316354 countsByYear W16083163542012 @default.
- W1608316354 countsByYear W16083163542013 @default.
- W1608316354 countsByYear W16083163542015 @default.
- W1608316354 countsByYear W16083163542016 @default.
- W1608316354 countsByYear W16083163542017 @default.
- W1608316354 countsByYear W16083163542023 @default.
- W1608316354 crossrefType "journal-article" @default.
- W1608316354 hasAuthorship W1608316354A5002037432 @default.
- W1608316354 hasAuthorship W1608316354A5009588472 @default.
- W1608316354 hasAuthorship W1608316354A5017226641 @default.
- W1608316354 hasAuthorship W1608316354A5031687021 @default.
- W1608316354 hasAuthorship W1608316354A5049641549 @default.
- W1608316354 hasAuthorship W1608316354A5058605320 @default.
- W1608316354 hasAuthorship W1608316354A5081723295 @default.
- W1608316354 hasBestOaLocation W16083163541 @default.
- W1608316354 hasConcept C104317684 @default.
- W1608316354 hasConcept C107459253 @default.
- W1608316354 hasConcept C143948831 @default.
- W1608316354 hasConcept C145103041 @default.
- W1608316354 hasConcept C148738053 @default.
- W1608316354 hasConcept C150194340 @default.
- W1608316354 hasConcept C168609215 @default.
- W1608316354 hasConcept C2778106681 @default.
- W1608316354 hasConcept C54355233 @default.
- W1608316354 hasConcept C86339819 @default.
- W1608316354 hasConcept C86803240 @default.
- W1608316354 hasConcept C95444343 @default.
- W1608316354 hasConceptScore W1608316354C104317684 @default.