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- W1608696359 abstract "The Apicomplexan parasites Toxoplasma gondii and Plasmodium species are obligate intracellular parasites that rely upon unique secretory organelles for invasion and other specialized functions. Data is emerging that proteases are critical for the biogenesis of micronemes and rhoptries, regulated secretory organelles reminiscent of dense core granules and secretory lysosomes of higher eukaryotes. Proteases targeted to the Plasmodium food vacuole, a unique organelle dedicated to hemoglobin degradation, are also critical to parasite survival. Thus study of the targeting and function of the proteases of the Apicomplexa provides a fascinating model system to understand regulated secretion and secretory organelle biogenesis." @default.
- W1608696359 created "2016-06-24" @default.
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- W1608696359 date "2004-10-20" @default.
- W1608696359 modified "2023-10-18" @default.
- W1608696359 title "Location, Location, Location: Trafficking and Function of Secreted Proteases of <i>Toxoplasma</i> and <i>Plasmodium</i>" @default.
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- W1608696359 doi "https://doi.org/10.1111/j.1600-0854.2004.00244.x" @default.
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