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- W160980706 abstract "Lipoprotein(a) [Lp(a)] is a unique lipoprotein with controversial functions. Lp(a) contains apolipoprotein(a) [apo(a)] covalently attached to apolipoprotein B on the low-density lipoprotein (LDL) particle. The distribution of blood Lp(a) concentrations in several populations have been found to be skewed with Lp(a) being mostly present at low level (0-200 mg/L). A high Lp(a) concentration (greater than 200 mg/L) in blood increases the risk of various vascular diseases including chronic heart disease, acute myocardial infarction and cerebral thrombosis. With Lp(a) potentially having such deleterious effects, there is a need to ask what are the evolutionary benefit(s) of Lp(a) to humans and other mammals that have it. Lp(a) has been reported to offer a number of benefits such as providing protection from LDL cholesterol and providing a source of cholesterol in wound tissue. Furthermore, some evidence is emerging that Lp(a) has anti-tumor properties. Other surveys have indicated that Lp(a) is advantageous because it promotes longevity. Lp(a) is only found in humans, old world monkeys and hedgehogs. Individuals who do not express Lp(a) do not show any disease symptoms, which indicates that Lp(a) is not essential for human life. It still remains unclear why mysterious Lp(a) has evolved and is present in humans." @default.
- W160980706 created "2016-06-24" @default.
- W160980706 creator A5017759094 @default.
- W160980706 date "2011-12-27" @default.
- W160980706 modified "2023-09-23" @default.
- W160980706 title "Lipoprotein(a) in vascular disease, cancer and longevity." @default.
- W160980706 cites W1485802716 @default.
- W160980706 cites W1489809204 @default.
- W160980706 cites W1501146982 @default.
- W160980706 cites W1588845829 @default.
- W160980706 cites W1605718906 @default.
- W160980706 cites W171081901 @default.
- W160980706 cites W1751375690 @default.
- W160980706 cites W1927986340 @default.
- W160980706 cites W1968471163 @default.
- W160980706 cites W1973135952 @default.
- W160980706 cites W1975168532 @default.
- W160980706 cites W1976360203 @default.
- W160980706 cites W1978139448 @default.
- W160980706 cites W1981039801 @default.
- W160980706 cites W1981135463 @default.
- W160980706 cites W1983055162 @default.
- W160980706 cites W1985477600 @default.
- W160980706 cites W1989069669 @default.
- W160980706 cites W1991341582 @default.
- W160980706 cites W1993729215 @default.
- W160980706 cites W1995859867 @default.
- W160980706 cites W1997354164 @default.
- W160980706 cites W1999895267 @default.
- W160980706 cites W2013525819 @default.
- W160980706 cites W2018608912 @default.
- W160980706 cites W2019295985 @default.
- W160980706 cites W2022642030 @default.
- W160980706 cites W2026057039 @default.
- W160980706 cites W2026524356 @default.
- W160980706 cites W2027439813 @default.
- W160980706 cites W2033903142 @default.
- W160980706 cites W2036170644 @default.
- W160980706 cites W2037186278 @default.
- W160980706 cites W2040247371 @default.
- W160980706 cites W2041218674 @default.
- W160980706 cites W2045854967 @default.
- W160980706 cites W2046913628 @default.
- W160980706 cites W2050216845 @default.
- W160980706 cites W2053607106 @default.
- W160980706 cites W2060008696 @default.
- W160980706 cites W2062008069 @default.
- W160980706 cites W2066303828 @default.
- W160980706 cites W2067017848 @default.
- W160980706 cites W2069096559 @default.
- W160980706 cites W2069981227 @default.
- W160980706 cites W2072829076 @default.
- W160980706 cites W2072928113 @default.
- W160980706 cites W2081254779 @default.
- W160980706 cites W2081572625 @default.
- W160980706 cites W2085959182 @default.
- W160980706 cites W2088625804 @default.
- W160980706 cites W2088704651 @default.
- W160980706 cites W2089610798 @default.
- W160980706 cites W2091767695 @default.
- W160980706 cites W2092426758 @default.
- W160980706 cites W2095210977 @default.
- W160980706 cites W2096751530 @default.
- W160980706 cites W2098152782 @default.
- W160980706 cites W2105359793 @default.
- W160980706 cites W2108284872 @default.
- W160980706 cites W2112722571 @default.
- W160980706 cites W2117988339 @default.
- W160980706 cites W2119720591 @default.
- W160980706 cites W2129006332 @default.
- W160980706 cites W2130483103 @default.
- W160980706 cites W2131798870 @default.
- W160980706 cites W2132618877 @default.
- W160980706 cites W2133278470 @default.
- W160980706 cites W2135804102 @default.
- W160980706 cites W2139143846 @default.
- W160980706 cites W2147029096 @default.
- W160980706 cites W2154977485 @default.
- W160980706 cites W2157251990 @default.
- W160980706 cites W2158046255 @default.
- W160980706 cites W2161779859 @default.
- W160980706 cites W2168683484 @default.
- W160980706 cites W2169635925 @default.
- W160980706 cites W2170183132 @default.
- W160980706 cites W2183925195 @default.
- W160980706 cites W2207166403 @default.
- W160980706 cites W2326789506 @default.
- W160980706 cites W2368946932 @default.
- W160980706 cites W2407121801 @default.
- W160980706 cites W310981707 @default.
- W160980706 cites W38448582 @default.
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