FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1609854108> ?p ?o ?g. }

• W1609854108 endingPage "6681" @default.
• W1609854108 startingPage "6677" @default.
• W1609854108 abstract "Memory T cells (mTC) express multiple chemokine receptors (including CCR4 and CCR6) that may potentially be involved in their arrest on inflamed endothelia. Herein, we specifically addressed whether CCR6 is required for mTC to arrest on TNF-alpha-activated human dermal microvascular endothelial cells (HDMEC) in vitro under shear stress conditions. Recombinant liver and activation-regulated chemokine (LARC)/CCL20 (a CCR6 ligand) induced firm arrest of cutaneous lymphocyte Ag(+) mTC in a flow chamber system using purified substrates. Strikingly, desensitization of CCR6 with LARC, but not thymus and activation-regulated chemokine/CCL17 or secondary lymphoid tissue chemokine/CCL21, caused a 50-75% decrease (p < 0. 001) in arrest of mTC on HDMEC, which was indistinguishable from the reduction observed when total mTC were treated with pertussis toxin (p > 0.5). CCR6-depleted mTC also had a markedly reduced ability to arrest on HDMEC. Our results suggest that LARC production by activated endothelial cells and CCR6 expression by mTC may be critical components in the pertussis toxin-sensitive arrest of mTC on activated HDMEC." @default.
• W1609854108 created "2016-06-24" @default.
• W1609854108 creator A5036139101 @default.
• W1609854108 creator A5045346465 @default.
• W1609854108 creator A5052989701 @default.
• W1609854108 creator A5078536489 @default.
• W1609854108 date "2000-12-15" @default.
• W1609854108 modified "2023-10-03" @default.
• W1609854108 title "Cutting Edge: C-C Chemokine Receptor 6 Is Essential for Arrest of a Subset of Memory T Cells on Activated Dermal Microvascular Endothelial Cells Under Physiologic Flow Conditions In Vitro" @default.
• W1609854108 cites W1534594872 @default.
• W1609854108 cites W1535141082 @default.
• W1609854108 cites W1537188001 @default.
• W1609854108 cites W1538469124 @default.
• W1609854108 cites W1539161723 @default.
• W1609854108 cites W1966010613 @default.
• W1609854108 cites W1971505103 @default.
• W1609854108 cites W1973312218 @default.
• W1609854108 cites W1984115097 @default.
• W1609854108 cites W2001433846 @default.
• W1609854108 cites W2016397844 @default.
• W1609854108 cites W2031311732 @default.
• W1609854108 cites W2059413226 @default.
• W1609854108 cites W2060338116 @default.
• W1609854108 cites W2089671691 @default.
• W1609854108 cites W2103384599 @default.
• W1609854108 cites W2129356601 @default.
• W1609854108 cites W2138769023 @default.
• W1609854108 cites W2147303583 @default.
• W1609854108 cites W2160129587 @default.
• W1609854108 cites W2166111489 @default.
• W1609854108 cites W2168089480 @default.
• W1609854108 cites W2170262191 @default.
• W1609854108 cites W4250106116 @default.
• W1609854108 cites W4313333699 @default.
• W1609854108 doi "https://doi.org/10.4049/jimmunol.165.12.6677" @default.
• W1609854108 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11120783" @default.
• W1609854108 hasPublicationYear "2000" @default.
• W1609854108 type Work @default.
• W1609854108 sameAs 1609854108 @default.
• W1609854108 citedByCount "108" @default.
• W1609854108 countsByYear W16098541082012 @default.
• W1609854108 countsByYear W16098541082013 @default.
• W1609854108 countsByYear W16098541082014 @default.
• W1609854108 countsByYear W16098541082015 @default.
• W1609854108 countsByYear W16098541082016 @default.
• W1609854108 countsByYear W16098541082017 @default.
• W1609854108 countsByYear W16098541082018 @default.
• W1609854108 countsByYear W16098541082020 @default.
• W1609854108 countsByYear W16098541082021 @default.
• W1609854108 countsByYear W16098541082022 @default.
• W1609854108 crossrefType "journal-article" @default.
• W1609854108 hasAuthorship W1609854108A5036139101 @default.
• W1609854108 hasAuthorship W1609854108A5045346465 @default.
• W1609854108 hasAuthorship W1609854108A5052989701 @default.
• W1609854108 hasAuthorship W1609854108A5078536489 @default.
• W1609854108 hasBestOaLocation W16098541081 @default.
• W1609854108 hasConcept C12823836 @default.
• W1609854108 hasConcept C128879288 @default.
• W1609854108 hasConcept C129013479 @default.
• W1609854108 hasConcept C13373296 @default.
• W1609854108 hasConcept C140944930 @default.
• W1609854108 hasConcept C143172330 @default.
• W1609854108 hasConcept C185592680 @default.
• W1609854108 hasConcept C186382791 @default.
• W1609854108 hasConcept C203014093 @default.
• W1609854108 hasConcept C2776914184 @default.
• W1609854108 hasConcept C502942594 @default.
• W1609854108 hasConcept C83360876 @default.
• W1609854108 hasConcept C86803240 @default.
• W1609854108 hasConcept C94205230 @default.
• W1609854108 hasConcept C95444343 @default.
• W1609854108 hasConceptScore W1609854108C12823836 @default.
• W1609854108 hasConceptScore W1609854108C128879288 @default.
• W1609854108 hasConceptScore W1609854108C129013479 @default.
• W1609854108 hasConceptScore W1609854108C13373296 @default.
• W1609854108 hasConceptScore W1609854108C140944930 @default.
• W1609854108 hasConceptScore W1609854108C143172330 @default.
• W1609854108 hasConceptScore W1609854108C185592680 @default.
• W1609854108 hasConceptScore W1609854108C186382791 @default.
• W1609854108 hasConceptScore W1609854108C203014093 @default.
• W1609854108 hasConceptScore W1609854108C2776914184 @default.
• W1609854108 hasConceptScore W1609854108C502942594 @default.
• W1609854108 hasConceptScore W1609854108C83360876 @default.
• W1609854108 hasConceptScore W1609854108C86803240 @default.
• W1609854108 hasConceptScore W1609854108C94205230 @default.
• W1609854108 hasConceptScore W1609854108C95444343 @default.
• W1609854108 hasIssue "12" @default.
• W1609854108 hasLocation W16098541081 @default.
• W1609854108 hasLocation W16098541082 @default.
• W1609854108 hasOpenAccess W1609854108 @default.
• W1609854108 hasPrimaryLocation W16098541081 @default.
• W1609854108 hasRelatedWork W1609854108 @default.
• W1609854108 hasRelatedWork W1990895486 @default.
• W1609854108 hasRelatedWork W2092305272 @default.
• W1609854108 hasRelatedWork W2133169003 @default.
• W1609854108 hasRelatedWork W2159865570 @default.
• W1609854108 hasRelatedWork W2315695983 @default.
• W1609854108 hasRelatedWork W2461493830 @default.

• next