FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W16103346> ?p ?o ?g. }

• W16103346 endingPage "3279" @default.
• W16103346 startingPage "3273" @default.
• W16103346 abstract "Abstract Therapy-related myelodysplasia (t-MDS) and acute myeloid leukemia (t-AML) after high-dose chemotherapy (HD-CT) and autologous stem cell transplantation (ASCT) for malignant diseases have become an important problem. The actuarial risk has varied, but has often been high if compared to the risk after conventional therapy. Prior chemotherapy with large cumulative doses of alkylating agents is the most important risk factor. In addition, patient age and previous radiotherapy, particularly the use of total body irradiation (TBI) in the preparative regimen for ASCT, have been identified as risk factors. In 3 studies, patients transplanted with CD34+ cells from peripheral blood after chemotherapy priming showed a higher risk of t-MDS or t-AML than patients transplanted with cells isolated from the bone marrow without priming. To what extent this higher risk relates to the prior therapy with a different contamination with preleukemic, hematopoietic precursors of the CD34+ cells obtained by the 2 methods, or is a direct result of chemotherapy priming, or of an increasing awareness of these complications, remains to be determined. The latent period from ASCT to t-MDS and t-AML has often been short, 12 months or less in 27% of the patients. Bone marrow pathology of early cases of t-MDS after ASCT has often been neither diagnostic nor prognostic, but most patients presented chromosome aberrations, primarily deletions or loss of the long arms of chromosomes 5 and 7. The prognosis was in general poor, although 17% with indolent t-MDS survived more than 18 months from diagnosis, and most of these presented a normal karyotype or a single chromosome aberration." @default.
• W16103346 created "2016-06-24" @default.
• W16103346 creator A5006055158 @default.
• W16103346 creator A5021191909 @default.
• W16103346 creator A5056500582 @default.
• W16103346 date "2000-06-01" @default.
• W16103346 modified "2023-10-02" @default.
• W16103346 title "Therapy-related acute myeloid leukemia and myelodysplasia after high-dose chemotherapy and autologous stem cell transplantation" @default.
• W16103346 cites W117509039 @default.
• W16103346 cites W1497143314 @default.
• W16103346 cites W1499089282 @default.
• W16103346 cites W160032427 @default.
• W16103346 cites W1754349841 @default.
• W16103346 cites W1785638885 @default.
• W16103346 cites W1796305773 @default.
• W16103346 cites W1833467461 @default.
• W16103346 cites W1846648891 @default.
• W16103346 cites W1849027585 @default.
• W16103346 cites W1856810180 @default.
• W16103346 cites W187238933 @default.
• W16103346 cites W1877303819 @default.
• W16103346 cites W1905293830 @default.
• W16103346 cites W1933695467 @default.
• W16103346 cites W1934485849 @default.
• W16103346 cites W1937538988 @default.
• W16103346 cites W1967127679 @default.
• W16103346 cites W1986873979 @default.
• W16103346 cites W1987992955 @default.
• W16103346 cites W1988948216 @default.
• W16103346 cites W2000397296 @default.
• W16103346 cites W2003999130 @default.
• W16103346 cites W2007532842 @default.
• W16103346 cites W2022449585 @default.
• W16103346 cites W2037341400 @default.
• W16103346 cites W2037735187 @default.
• W16103346 cites W2037830358 @default.
• W16103346 cites W2051139978 @default.
• W16103346 cites W2061628268 @default.
• W16103346 cites W2064112957 @default.
• W16103346 cites W2069895841 @default.
• W16103346 cites W2076426515 @default.
• W16103346 cites W2094663887 @default.
• W16103346 cites W2131853861 @default.
• W16103346 cites W2134911461 @default.
• W16103346 cites W2207262939 @default.
• W16103346 cites W2229863299 @default.
• W16103346 cites W2245871225 @default.
• W16103346 cites W2274830100 @default.
• W16103346 cites W2288473528 @default.
• W16103346 cites W2288605453 @default.
• W16103346 cites W2304365550 @default.
• W16103346 cites W2316796638 @default.
• W16103346 cites W2316917533 @default.
• W16103346 cites W2322312023 @default.
• W16103346 cites W2331042177 @default.
• W16103346 cites W2395585278 @default.
• W16103346 cites W2407983088 @default.
• W16103346 cites W2465708327 @default.
• W16103346 cites W254205321 @default.
• W16103346 cites W2611745499 @default.
• W16103346 cites W39618587 @default.
• W16103346 cites W4235885205 @default.
• W16103346 cites W4240026283 @default.
• W16103346 cites W4253540948 @default.
• W16103346 cites W4253916874 @default.
• W16103346 doi "https://doi.org/10.1182/blood.v95.11.3273" @default.
• W16103346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10828005" @default.
• W16103346 hasPublicationYear "2000" @default.
• W16103346 type Work @default.
• W16103346 sameAs 16103346 @default.
• W16103346 citedByCount "217" @default.
• W16103346 countsByYear W161033462012 @default.
• W16103346 countsByYear W161033462013 @default.
• W16103346 countsByYear W161033462014 @default.
• W16103346 countsByYear W161033462015 @default.
• W16103346 countsByYear W161033462016 @default.
• W16103346 countsByYear W161033462017 @default.
• W16103346 countsByYear W161033462018 @default.
• W16103346 countsByYear W161033462019 @default.
• W16103346 countsByYear W161033462020 @default.
• W16103346 countsByYear W161033462021 @default.
• W16103346 countsByYear W161033462022 @default.
• W16103346 countsByYear W161033462023 @default.
• W16103346 crossrefType "journal-article" @default.
• W16103346 hasAuthorship W16103346A5006055158 @default.
• W16103346 hasAuthorship W16103346A5021191909 @default.
• W16103346 hasAuthorship W16103346A5056500582 @default.
• W16103346 hasConcept C10205521 @default.
• W16103346 hasConcept C126322002 @default.
• W16103346 hasConcept C143998085 @default.
• W16103346 hasConcept C203014093 @default.
• W16103346 hasConcept C2776694085 @default.
• W16103346 hasConcept C2776755627 @default.
• W16103346 hasConcept C2777408962 @default.
• W16103346 hasConcept C2778336483 @default.
• W16103346 hasConcept C2778461978 @default.
• W16103346 hasConcept C2778729363 @default.
• W16103346 hasConcept C2778880498 @default.

• next