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- W161096252 abstract "Publisher SummaryThere are five major types of herpes virus known capable of inducing human diseases. Herpes viruses have been associated with many diseases, but there are no specific anti-herpes agents currently used in the clinic that lack toxicity to patients. To develop these agents and to know how to use these agents effectively, more of the biochemistry of herpes virus infected and uninfected cells are needed. It should be recognized that each type of herpes virus has their own unique set of biochemical parameters; however, they share some common entities that could be utilized for the development of antiherpes agents with wider spectrum. Herpes simplex virus resistant to thymidine analogs and that resistant to phosphonoacetic acid have already been isolated. Therefore, for the future treatment of herpes associated diseases, specific antiherpes agents that exert their actions independently should be developed and used in combination to avoid the complications of drug resistance through the mechanism of virus mutation." @default.
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- W161096252 date "1979-01-01" @default.
- W161096252 modified "2023-10-16" @default.
- W161096252 title "STRATEGY FOR THE DEVELOPMENT OF SELECTIVE ANTIHERPES VIRUS AGENTS BASED ON THE UNIQUE PROPERTIES OF VIRAL INDUCED ENZYMES—THYMIDINE KINASE, DNase AND DNA POLYMERASE" @default.
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- W161096252 doi "https://doi.org/10.1016/b978-0-08-024384-9.50025-7" @default.
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