FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W161254365> ?p ?o ?g. }

• W161254365 endingPage "144" @default.
• W161254365 startingPage "134" @default.
• W161254365 abstract "This prospective, observational study in 988 asymptomatic or symptomatic low-risk patients without prior coronary artery disease was conducted to define the relative value of coronary artery calcium score (CACS), exercise treadmill testing (ETT), and stress myocardial perfusion single-photon emission computed tomography (SPECT) variables in predicting long-term risk stratification. CACS, ETT, and stress myocardial perfusion SPECT results predict patients' outcome. There are currently no data comparing their relative value in long-term risk stratification. Patients were stratified by Framingham risk score (FRS), with a median follow-up of 6.9 years. Cardiac events were defined as a composite of cardiac death, nonfatal myocardial infarction, and the need for coronary revascularization. Most patients (87%) were considered appropriate candidates for functional testing as defined by current appropriate use criteria. The long-term cardiac event rate was 11.2% (1.6% per year). Multivariate risk predictors in all patients and in the appropriate use cohort were abnormal SPECT (hazard ratio [HR]: 1.83 and 1.99), ETT ischemia (HR: 1.70 and 1.76), decreasing exercise capacity (HR: 1.11 and 1.17), decreasing Duke treadmill score (HR: 1.07 for both), and CACS severity (HR: 1.29 for both), respectively. Throughout the 10-year follow-up, CACS improved risk prediction, with event rates ranging from 0.6% per year (CACS ≤10) to 3.7% per year (CACS >400) (p < 0.0001). CACS also improved risk prediction in all patients, in the appropriate use cohort and among those with low-risk ETT and SPECT results (all, p < 0.001). Area under the receiver-operating characteristic curve was increased when CACS variables (from 0.63 to 0.70; p = 0.01) but not ETT variables (from 0.63 to 0.65) were added to FRS. Moreover, net reclassification improvement was significantly increased when CACS was added to FRS + functional variables in all patients and in the appropriate use cohort (both, p < 0.0001). CACS significantly improved long-term risk stratification beyond FRS, ETT, and SPECT results across the spectrum of clinical risk and importantly even among those who are currently considered appropriate candidates for functional testing or have low-risk functional test results. Our findings support CACS as a first-line test over ETT or SPECT for accurately assessing long-term risk in such patients." @default.
• W161254365 created "2016-06-24" @default.
• W161254365 creator A5018711959 @default.
• W161254365 creator A5033395691 @default.
• W161254365 creator A5035785777 @default.
• W161254365 creator A5076951358 @default.
• W161254365 creator A5083179513 @default.
• W161254365 creator A5087762819 @default.
• W161254365 creator A5091733704 @default.
• W161254365 date "2015-02-01" @default.
• W161254365 modified "2023-09-30" @default.
• W161254365 title "Value of CACS Compared With ETT and Myocardial Perfusion Imaging for Predicting Long-Term Cardiac Outcome in Asymptomatic and Symptomatic Patients at Low Risk for Coronary Disease" @default.
• W161254365 cites W118162583 @default.
• W161254365 cites W158880344 @default.
• W161254365 cites W1600722282 @default.
• W161254365 cites W166112863 @default.
• W161254365 cites W1969678022 @default.
• W161254365 cites W1971474283 @default.
• W161254365 cites W1977834199 @default.
• W161254365 cites W1986150026 @default.
• W161254365 cites W1996082994 @default.
• W161254365 cites W2005751258 @default.
• W161254365 cites W2012037442 @default.
• W161254365 cites W2023486228 @default.
• W161254365 cites W2026766157 @default.
• W161254365 cites W2053760965 @default.
• W161254365 cites W2058733233 @default.
• W161254365 cites W2112316706 @default.
• W161254365 cites W2122691873 @default.
• W161254365 cites W2133211347 @default.
• W161254365 cites W2547350832 @default.
• W161254365 cites W3119924594 @default.
• W161254365 cites W4231927329 @default.
• W161254365 doi "https://doi.org/10.1016/j.jcmg.2014.11.008" @default.
• W161254365 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25677886" @default.
• W161254365 hasPublicationYear "2015" @default.
• W161254365 type Work @default.
• W161254365 sameAs 161254365 @default.
• W161254365 citedByCount "60" @default.
• W161254365 countsByYear W1612543652015 @default.
• W161254365 countsByYear W1612543652016 @default.
• W161254365 countsByYear W1612543652017 @default.
• W161254365 countsByYear W1612543652018 @default.
• W161254365 countsByYear W1612543652019 @default.
• W161254365 countsByYear W1612543652020 @default.
• W161254365 countsByYear W1612543652021 @default.
• W161254365 countsByYear W1612543652022 @default.
• W161254365 countsByYear W1612543652023 @default.
• W161254365 crossrefType "journal-article" @default.
• W161254365 hasAuthorship W161254365A5018711959 @default.
• W161254365 hasAuthorship W161254365A5033395691 @default.
• W161254365 hasAuthorship W161254365A5035785777 @default.
• W161254365 hasAuthorship W161254365A5076951358 @default.
• W161254365 hasAuthorship W161254365A5083179513 @default.
• W161254365 hasAuthorship W161254365A5087762819 @default.
• W161254365 hasAuthorship W161254365A5091733704 @default.
• W161254365 hasBestOaLocation W1612543651 @default.
• W161254365 hasConcept C11783203 @default.
• W161254365 hasConcept C126322002 @default.
• W161254365 hasConcept C164705383 @default.
• W161254365 hasConcept C207103383 @default.
• W161254365 hasConcept C2777910003 @default.
• W161254365 hasConcept C2778213512 @default.
• W161254365 hasConcept C2778405248 @default.
• W161254365 hasConcept C2779134260 @default.
• W161254365 hasConcept C44249647 @default.
• W161254365 hasConcept C500558357 @default.
• W161254365 hasConcept C50382708 @default.
• W161254365 hasConcept C71924100 @default.
• W161254365 hasConcept C72563966 @default.
• W161254365 hasConceptScore W161254365C11783203 @default.
• W161254365 hasConceptScore W161254365C126322002 @default.
• W161254365 hasConceptScore W161254365C164705383 @default.
• W161254365 hasConceptScore W161254365C207103383 @default.
• W161254365 hasConceptScore W161254365C2777910003 @default.
• W161254365 hasConceptScore W161254365C2778213512 @default.
• W161254365 hasConceptScore W161254365C2778405248 @default.
• W161254365 hasConceptScore W161254365C2779134260 @default.
• W161254365 hasConceptScore W161254365C44249647 @default.
• W161254365 hasConceptScore W161254365C500558357 @default.
• W161254365 hasConceptScore W161254365C50382708 @default.
• W161254365 hasConceptScore W161254365C71924100 @default.
• W161254365 hasConceptScore W161254365C72563966 @default.
• W161254365 hasIssue "2" @default.
• W161254365 hasLocation W1612543651 @default.
• W161254365 hasLocation W1612543652 @default.
• W161254365 hasOpenAccess W161254365 @default.
• W161254365 hasPrimaryLocation W1612543651 @default.
• W161254365 hasRelatedWork W1977729419 @default.
• W161254365 hasRelatedWork W2049849716 @default.
• W161254365 hasRelatedWork W2076222267 @default.
• W161254365 hasRelatedWork W2089715561 @default.
• W161254365 hasRelatedWork W2115405528 @default.
• W161254365 hasRelatedWork W2417414779 @default.
• W161254365 hasRelatedWork W2773578431 @default.
• W161254365 hasRelatedWork W2790353319 @default.
• W161254365 hasRelatedWork W2980864243 @default.
• W161254365 hasRelatedWork W3084364512 @default.

• next