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• W161423276 abstract "In water-breathing fish, neuroepithelial cells located in the gills and innervated by the IX and X cranial nerves appear to be the primary, if not exclusive chemoreceptors detecting changes in water CO 2 levels and stimulating increases in ventilation frequency and/or amplitude. Receptors sensing changes in arterial blood pH may also be involved in producing similar reflex responses. In air-breathing fish, the input from these receptors leads to increase in air breathing rather than gill ventilation when levels of aquatic CO 2 rise sufficiently. In lungfish and in some other air-breathing fish, central (within the brainstem) CO 2 /H + -sensitive chemoreceptors also appear to be involved in producing respiratory reflexes. The only CO 2 /H + chemoreceptors for which the transduction mechanism has been studied at the cellular level are the neuroepithelial cells within the gills. A subset of these cells are depolarized by CO 2 due to the closing of a background K + channel involving a mechanism that depends, in part, on carbonic anhydrase. In some, but not all, cases, this occurs in cells that also respond to changes in O 2 ." @default.
• W161423276 created "2016-06-24" @default.
• W161423276 creator A5080793934 @default.
• W161423276 date "2011-01-01" @default.
• W161423276 modified "2023-09-28" @default.
• W161423276 title "CONTROL OF RESPIRATION | The Ventilatory Response to CO2/H+" @default.
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• W161423276 doi "https://doi.org/10.1016/b978-0-12-374553-8.00230-6" @default.
• W161423276 hasPublicationYear "2011" @default.
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