Matches in SemOpenAlex for { <https://semopenalex.org/work/W1616173504> ?p ?o ?g. }
- W1616173504 endingPage "72" @default.
- W1616173504 startingPage "165" @default.
- W1616173504 abstract "Thrombophilia is a multifactorial predisposition for thromboembolism affecting about a tenth of any population. We investigated whether genetic counseling combined with molecular testing for two common dominant mutations (coagulation factor V Leiden and prothrombin G20210A) may increase prevention of venous thromboembolic incidents in individuals with a positive family history compared to the general population.Mutation detection was carried out by Restriction Fragment Length Polymorphism analysis in DNA samples of 96 unrelated healthy Greeks (group A) who asked for genetic counseling for various reasons and had at least two relatives with thromboembolic incidents and 100 unrelated healthy Greeks (group B).In group A, both mutations were detected at five-fold higher frequencies (33.33% for Leiden and 19.79% for G20210A) compared to group B, which had frequencies typically found in the Greek population (6% and 4%, respectively).In populations with a high prevalence for these two common mutations, genetic counseling and molecular testing of at-risk individuals may significantly increase prevention of thromboembolic disease." @default.
- W1616173504 created "2016-06-24" @default.
- W1616173504 creator A5017484449 @default.
- W1616173504 creator A5044129248 @default.
- W1616173504 creator A5056845106 @default.
- W1616173504 creator A5077407698 @default.
- W1616173504 creator A5090677155 @default.
- W1616173504 date "2012-01-03" @default.
- W1616173504 modified "2023-09-26" @default.
- W1616173504 title "Potential prevention of thromboembolism by genetic counseling and testing for two common thrombophilia mutations." @default.
- W1616173504 cites W1524603322 @default.
- W1616173504 cites W1531281563 @default.
- W1616173504 cites W1548595903 @default.
- W1616173504 cites W1579158654 @default.
- W1616173504 cites W1964769191 @default.
- W1616173504 cites W1965958910 @default.
- W1616173504 cites W1967655607 @default.
- W1616173504 cites W1972834727 @default.
- W1616173504 cites W1980669153 @default.
- W1616173504 cites W1985461293 @default.
- W1616173504 cites W1989733945 @default.
- W1616173504 cites W1989953022 @default.
- W1616173504 cites W1993729059 @default.
- W1616173504 cites W2007702636 @default.
- W1616173504 cites W2015648276 @default.
- W1616173504 cites W2019428942 @default.
- W1616173504 cites W2024331650 @default.
- W1616173504 cites W2035708142 @default.
- W1616173504 cites W2037170514 @default.
- W1616173504 cites W2038799381 @default.
- W1616173504 cites W2047107520 @default.
- W1616173504 cites W2047648470 @default.
- W1616173504 cites W2051813173 @default.
- W1616173504 cites W2054327324 @default.
- W1616173504 cites W2054904212 @default.
- W1616173504 cites W2060447792 @default.
- W1616173504 cites W2066688265 @default.
- W1616173504 cites W2071378775 @default.
- W1616173504 cites W2104062454 @default.
- W1616173504 cites W2111726984 @default.
- W1616173504 cites W2115885282 @default.
- W1616173504 cites W2116355717 @default.
- W1616173504 cites W2118445599 @default.
- W1616173504 cites W2119389524 @default.
- W1616173504 cites W2133333494 @default.
- W1616173504 cites W2136998269 @default.
- W1616173504 cites W2138985259 @default.
- W1616173504 cites W2142111605 @default.
- W1616173504 cites W2145533041 @default.
- W1616173504 cites W2154023713 @default.
- W1616173504 cites W2164328427 @default.
- W1616173504 cites W2317291830 @default.
- W1616173504 cites W2318577668 @default.
- W1616173504 cites W2320717186 @default.
- W1616173504 cites W2324329834 @default.
- W1616173504 cites W2339305503 @default.
- W1616173504 cites W2413208961 @default.
- W1616173504 cites W2413850721 @default.
- W1616173504 cites W2415264124 @default.
- W1616173504 cites W75980162 @default.
- W1616173504 cites W1895289762 @default.
- W1616173504 cites W2613821454 @default.
- W1616173504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22210734" @default.
- W1616173504 hasPublicationYear "2012" @default.
- W1616173504 type Work @default.
- W1616173504 sameAs 1616173504 @default.
- W1616173504 citedByCount "3" @default.
- W1616173504 countsByYear W16161735042012 @default.
- W1616173504 countsByYear W16161735042015 @default.
- W1616173504 countsByYear W16161735042018 @default.
- W1616173504 crossrefType "journal-article" @default.
- W1616173504 hasAuthorship W1616173504A5017484449 @default.
- W1616173504 hasAuthorship W1616173504A5044129248 @default.
- W1616173504 hasAuthorship W1616173504A5056845106 @default.
- W1616173504 hasAuthorship W1616173504A5077407698 @default.
- W1616173504 hasAuthorship W1616173504A5090677155 @default.
- W1616173504 hasConcept C104317684 @default.
- W1616173504 hasConcept C126322002 @default.
- W1616173504 hasConcept C135763542 @default.
- W1616173504 hasConcept C168007829 @default.
- W1616173504 hasConcept C2777175894 @default.
- W1616173504 hasConcept C2777872019 @default.
- W1616173504 hasConcept C2778382381 @default.
- W1616173504 hasConcept C2780011451 @default.
- W1616173504 hasConcept C2780673598 @default.
- W1616173504 hasConcept C2780842393 @default.
- W1616173504 hasConcept C2780868729 @default.
- W1616173504 hasConcept C2781179581 @default.
- W1616173504 hasConcept C2908647359 @default.
- W1616173504 hasConcept C54355233 @default.
- W1616173504 hasConcept C71924100 @default.
- W1616173504 hasConcept C80227256 @default.
- W1616173504 hasConcept C86803240 @default.
- W1616173504 hasConcept C90924648 @default.
- W1616173504 hasConcept C99454951 @default.
- W1616173504 hasConceptScore W1616173504C104317684 @default.
- W1616173504 hasConceptScore W1616173504C126322002 @default.
- W1616173504 hasConceptScore W1616173504C135763542 @default.