Matches in SemOpenAlex for { <https://semopenalex.org/work/W1617342272> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1617342272 abstract "Chronic red blood cell (RBC) transfusion is employed for a wide range of sickle cell disease complications, ranging from primary and secondary stroke prophylaxis to prevention of painful vaso-occlusive episodes. Currently different methods are employed by centers for chronic transfusion that include simple, automated and partial manual RBC exchange transfusion. A retrospective cohort study of two different manual RBC exchange transfusion methods was conducted between two comprehensive care centers in Toronto, ON, Canada and London, United Kingdom in 19 and 21 sickle cell disease adults, respectively. London used a weight-based protocol, while Toronto used a unit-based method. Our results indicated that sickle cell disease patients utilizing a weight-based method are more often unable to achieve the prescribed Hb S (HBB: c.20A > T) target compared to the unit-based method (90.0 vs. 53.0% in the weight-based and unit-based methods, respectively, p = 0.0123). On multivariable logistic regression, none of the covariates examined was found to influence the ability to achieve the prescribed Hb S target after accounting for the exchange transfusion method. Mean interval of exchange sessions, session duration, total units of packed RBC, volume of blood used by body weight each year, the mean post exchange hematocrit [or packed cell volume (PCV)] and ferritin change were similar in both cohorts. In conclusion, the unit-based method was more effective at maintaining the prescribed Hb S target." @default.
- W1617342272 created "2016-06-24" @default.
- W1617342272 creator A5010415710 @default.
- W1617342272 creator A5053253072 @default.
- W1617342272 creator A5057936988 @default.
- W1617342272 creator A5064622256 @default.
- W1617342272 creator A5084047203 @default.
- W1617342272 date "2015-06-26" @default.
- W1617342272 modified "2023-09-27" @default.
- W1617342272 title "Optimal Manual Exchange Transfusion Protocol for Sickle Cell Disease: A Retrospective Comparison of Two Comprehensive Care Centers in the United Kingdom and Canada" @default.
- W1617342272 cites W1498156640 @default.
- W1617342272 cites W1576345300 @default.
- W1617342272 cites W1972728922 @default.
- W1617342272 cites W1973288600 @default.
- W1617342272 cites W1997713243 @default.
- W1617342272 cites W2036000990 @default.
- W1617342272 cites W2038580441 @default.
- W1617342272 cites W2049045569 @default.
- W1617342272 cites W2069201334 @default.
- W1617342272 cites W2076949422 @default.
- W1617342272 cites W2082296736 @default.
- W1617342272 cites W2094305614 @default.
- W1617342272 cites W2095095757 @default.
- W1617342272 cites W2126956249 @default.
- W1617342272 cites W2127432854 @default.
- W1617342272 cites W2151664585 @default.
- W1617342272 cites W2166545857 @default.
- W1617342272 cites W2541294359 @default.
- W1617342272 cites W2551029062 @default.
- W1617342272 cites W3141197395 @default.
- W1617342272 doi "https://doi.org/10.3109/03630269.2015.1057734" @default.
- W1617342272 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26114740" @default.
- W1617342272 hasPublicationYear "2015" @default.
- W1617342272 type Work @default.
- W1617342272 sameAs 1617342272 @default.
- W1617342272 citedByCount "4" @default.
- W1617342272 countsByYear W16173422722016 @default.
- W1617342272 countsByYear W16173422722017 @default.
- W1617342272 countsByYear W16173422722020 @default.
- W1617342272 crossrefType "journal-article" @default.
- W1617342272 hasAuthorship W1617342272A5010415710 @default.
- W1617342272 hasAuthorship W1617342272A5053253072 @default.
- W1617342272 hasAuthorship W1617342272A5057936988 @default.
- W1617342272 hasAuthorship W1617342272A5064622256 @default.
- W1617342272 hasAuthorship W1617342272A5084047203 @default.
- W1617342272 hasConcept C126322002 @default.
- W1617342272 hasConcept C141071460 @default.
- W1617342272 hasConcept C151956035 @default.
- W1617342272 hasConcept C167135981 @default.
- W1617342272 hasConcept C187212893 @default.
- W1617342272 hasConcept C194828623 @default.
- W1617342272 hasConcept C2779042277 @default.
- W1617342272 hasConcept C2779134260 @default.
- W1617342272 hasConcept C2780014101 @default.
- W1617342272 hasConcept C71924100 @default.
- W1617342272 hasConcept C72563966 @default.
- W1617342272 hasConceptScore W1617342272C126322002 @default.
- W1617342272 hasConceptScore W1617342272C141071460 @default.
- W1617342272 hasConceptScore W1617342272C151956035 @default.
- W1617342272 hasConceptScore W1617342272C167135981 @default.
- W1617342272 hasConceptScore W1617342272C187212893 @default.
- W1617342272 hasConceptScore W1617342272C194828623 @default.
- W1617342272 hasConceptScore W1617342272C2779042277 @default.
- W1617342272 hasConceptScore W1617342272C2779134260 @default.
- W1617342272 hasConceptScore W1617342272C2780014101 @default.
- W1617342272 hasConceptScore W1617342272C71924100 @default.
- W1617342272 hasConceptScore W1617342272C72563966 @default.
- W1617342272 hasLocation W16173422721 @default.
- W1617342272 hasLocation W16173422722 @default.
- W1617342272 hasOpenAccess W1617342272 @default.
- W1617342272 hasPrimaryLocation W16173422721 @default.
- W1617342272 hasRelatedWork W1654731067 @default.
- W1617342272 hasRelatedWork W1764651538 @default.
- W1617342272 hasRelatedWork W1911865486 @default.
- W1617342272 hasRelatedWork W2039749549 @default.
- W1617342272 hasRelatedWork W2089259280 @default.
- W1617342272 hasRelatedWork W2121464179 @default.
- W1617342272 hasRelatedWork W2325756079 @default.
- W1617342272 hasRelatedWork W2394678723 @default.
- W1617342272 hasRelatedWork W2539149546 @default.
- W1617342272 hasRelatedWork W2595077035 @default.
- W1617342272 hasRelatedWork W2890497792 @default.
- W1617342272 hasRelatedWork W2899743508 @default.
- W1617342272 hasRelatedWork W2980151545 @default.
- W1617342272 hasRelatedWork W2987689288 @default.
- W1617342272 hasRelatedWork W3031434457 @default.
- W1617342272 hasRelatedWork W3080550293 @default.
- W1617342272 hasRelatedWork W3082506878 @default.
- W1617342272 hasRelatedWork W3094423778 @default.
- W1617342272 hasRelatedWork W2285530119 @default.
- W1617342272 hasRelatedWork W2312349890 @default.
- W1617342272 isParatext "false" @default.
- W1617342272 isRetracted "false" @default.
- W1617342272 magId "1617342272" @default.
- W1617342272 workType "article" @default.