Matches in SemOpenAlex for { <https://semopenalex.org/work/W161821> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W161821 abstract "Introduction To obtain an insight into mechanisms of the myocardium hypertrophy, we developed a new animal model. Methods Male Wistar rats were randomly assigned into a group for sham operation (sham group) and a group for venous occlusion in the hindlimb (experimental group; n= 7 for each group). 14 days after the operation, heart was dissected out and weighed. The relative content of heat shock protein-72 (HSP-72) and heat shock cognate protein-70 (Hsc-70), and the expressions of IGF-1, mechano growth factor (MGF), a1(1) procollagen, myostatin, nitric oxide synthase-1 and 2 (NOS-1 and NOS-2) mRNA were examined. Also, myocardium nitric oxide (NO) concentration was measured. For histological analyses, Hematoxylin/ Eosin (H&E), Oil Red O, Van Gieson and Elastica stains were made. Results The venous occlusion caused hypertrophy of the cardiac muscle (left ventricle), in which the expressions of IGF-1, a1(1) procollagen, and NOS-2 increased, whereas that of MGF, and the relative content of HSP-72 and NO concentration decreased. Elastica stain exhibited dense regions in the hypertrophied cardiac muscle. Conclusion Increase in peripheral vascular resistance causes myocardial hypertrophy and fibrosis associated with changes in heat shock protein and growth factors." @default.
- W161821 created "2016-06-24" @default.
- W161821 creator A5014743812 @default.
- W161821 creator A5020593496 @default.
- W161821 date "2006-03-01" @default.
- W161821 modified "2023-10-03" @default.
- W161821 title "Peripheral blood‐flow restriction caused hypertrophy associated with decreased HSP‐72 and fibrosis in rat myocardium" @default.
- W161821 doi "https://doi.org/10.1096/fasebj.20.5.a1448" @default.
- W161821 hasPublicationYear "2006" @default.
- W161821 type Work @default.
- W161821 sameAs 161821 @default.
- W161821 citedByCount "0" @default.
- W161821 crossrefType "journal-article" @default.
- W161821 hasAuthorship W161821A5014743812 @default.
- W161821 hasAuthorship W161821A5020593496 @default.
- W161821 hasConcept C104317684 @default.
- W161821 hasConcept C126322002 @default.
- W161821 hasConcept C134018914 @default.
- W161821 hasConcept C167414201 @default.
- W161821 hasConcept C185592680 @default.
- W161821 hasConcept C205260736 @default.
- W161821 hasConcept C2777622882 @default.
- W161821 hasConcept C2778921608 @default.
- W161821 hasConcept C2780559512 @default.
- W161821 hasConcept C2781300812 @default.
- W161821 hasConcept C519581460 @default.
- W161821 hasConcept C55493867 @default.
- W161821 hasConcept C71924100 @default.
- W161821 hasConceptScore W161821C104317684 @default.
- W161821 hasConceptScore W161821C126322002 @default.
- W161821 hasConceptScore W161821C134018914 @default.
- W161821 hasConceptScore W161821C167414201 @default.
- W161821 hasConceptScore W161821C185592680 @default.
- W161821 hasConceptScore W161821C205260736 @default.
- W161821 hasConceptScore W161821C2777622882 @default.
- W161821 hasConceptScore W161821C2778921608 @default.
- W161821 hasConceptScore W161821C2780559512 @default.
- W161821 hasConceptScore W161821C2781300812 @default.
- W161821 hasConceptScore W161821C519581460 @default.
- W161821 hasConceptScore W161821C55493867 @default.
- W161821 hasConceptScore W161821C71924100 @default.
- W161821 hasIssue "5" @default.
- W161821 hasLocation W1618211 @default.
- W161821 hasOpenAccess W161821 @default.
- W161821 hasPrimaryLocation W1618211 @default.
- W161821 hasRelatedWork W1623258072 @default.
- W161821 hasRelatedWork W1779480512 @default.
- W161821 hasRelatedWork W1972190589 @default.
- W161821 hasRelatedWork W2008087125 @default.
- W161821 hasRelatedWork W2087337247 @default.
- W161821 hasRelatedWork W2089295326 @default.
- W161821 hasRelatedWork W2091504832 @default.
- W161821 hasRelatedWork W2093911704 @default.
- W161821 hasRelatedWork W2748952813 @default.
- W161821 hasRelatedWork W4248549364 @default.
- W161821 hasVolume "20" @default.
- W161821 isParatext "false" @default.
- W161821 isRetracted "false" @default.
- W161821 magId "161821" @default.
- W161821 workType "article" @default.