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- W1619408088 abstract "Our setup has been devised in which the spatial focus and the interference condition coincide at an assumed average refractive index of the sample, independently of the position /spl Delta/z/sub Fiber/,, of the fiber tip which causes the depth scanning. Local deviations in refractive index on the order of 25 /spl mu/m can be tracked by small position changes /spl Delta/Z/sub L1/ of one lens within the sample arm. Depending on the type of skin, refractive indices can be evaluated down to 400 /spl mu/m. The hydration level could clearly be delineated as it was demonstrated in the vicinity of a sweatgland duct in a palm. Images with a resolution of around 5 /spl mu/m have been obtained from various sites of the body. Beyond high resolution morphology in OCT images, additional local physical parameters can be desired for cosmetics/pharmaceutical and medical applications. Spatially confined refractive indices have been shown to provide a distribution map of moisture levels. Further studies (not shown) exhibit effects of hydration cremes. In skin disease characterization refractive index distribution may supplement clinical diagnosis." @default.
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- W1619408088 date "2003-06-25" @default.
- W1619408088 modified "2023-09-26" @default.
- W1619408088 title "Optical coherence tomography: state of the art" @default.
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- W1619408088 doi "https://doi.org/10.1109/isbi.2002.1029203" @default.
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