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• W1621387815 abstract "Hamiltonian path problem (HPP) is known to be in the problem class NP-complete. In this paper, a DNA origami-based method for solving the HPP was described. Among the various predefined 2D nanostructures created by DNA origami technology, a square shaped DNA origami body with decoration of numbers was selected for coding the vertexes while their single-stranded arms coded the paths. Because these arms could hybridize with their corresponding ones in the solution, all the paths with possibility would exist after annealing. Take advantage of magnetic beads and gel electrophoresis, the shortest path that pass each vertex once for HPP could easily found under the atomic force microscope. This method not only simplified the experimental procedures for solving the HPP but obtained a direct and readable result, which could also be applied to other problems requiring a massive parallelism in computation." @default.
• W1621387815 created "2016-06-24" @default.
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• W1621387815 date "2015-11-01" @default.
• W1621387815 modified "2023-09-26" @default.
• W1621387815 title "A “DNA origami”-based approach to the solution of Hamilton path problem" @default.
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• W1621387815 doi "https://doi.org/10.1360/n032015-00035" @default.
• W1621387815 hasPublicationYear "2015" @default.
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