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• W1622457845 startingPage "14185" @default.
• W1622457845 abstract "Although adaptive evolution is thought to depend primarily on mutations of small effect, major gene effects may underlie many of the important differences observed among species in nature. The Mexican axolotl ( Ambystoma mexicanum ) has a derived mode of development that is characterized by metamorphic failure (paedomorphosis), an adaptation for an entirely aquatic life cycle. By using an interspecific crossing design and genetic linkage analysis, a major quantitative trait locus for expression of metamorphosis was identified in a local map of amplified fragment length polymorphisms. These data are consistent with a major gene hypothesis for the evolution of paedomorphosis in A. mexicanum ." @default.
• W1622457845 created "2016-06-24" @default.
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• W1622457845 creator A5061975048 @default.
• W1622457845 date "1997-12-09" @default.
• W1622457845 modified "2023-10-03" @default.
• W1622457845 title "Adaptive evolution via a major gene effect: Paedomorphosis in the Mexican axolotl" @default.
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• W1622457845 doi "https://doi.org/10.1073/pnas.94.25.14185" @default.
• W1622457845 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/28454" @default.
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