FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W16228589> ?p ?o ?g. }

• W16228589 endingPage "34" @default.
• W16228589 startingPage "27" @default.
• W16228589 abstract "Posttraumatic epileptic seizures have an incidence of about 10% in series of severe head injuries. Control of “early seizures”, i.e. those occurring in the first week after injury, is mandatory. Attacks, especially if recurrent, may add secondary damage to the injured brain: intravenous phenythoin with therapeutic plasma level allows control of the attacks. Seizures occurring months or years after injury are called “late seizures”: recurring “late seizures” make up the clinical syndrome of “posttraumatic epilepsy”. “Prophylaxis” should mean that drug treatment, given for a more or less prolonged period of time, blocks permanently the ripening of the epileptogenic foci avoiding the occurrence of seizures. In animal “prophylaxis” by antiepileptic drugs seems efficacious in many experimental models including iron induced epilepsy which is considered a model of posttraumatic epilepsy and vice versa. In the human being “prophylaxis” has been attempted with: phenytoin, phenobarbital, carbamazepine, valproate but without success. During treatment period the occurrence of seizures is prevented but, after discontinuation of the drug, seizures occur just as in non treated patients. The ripening of the epileptic focus in posttraumatic epilepsy, as in iron induced epilepsy, seems to be due to a cascade of events beginning with haemorrhage, haemolysis, iron or heme compound liberation, free radical formation, peroxidation and cell death. Experimentally free radical scavengers and antiperoxidants have marked prophylactic effect. Some of them (phosphate diester of vitamin E and C, melatonin, vanillyl alcohol) may be employed in clinical practice, but up to date there is no controlled study in human beings." @default.
• W16228589 created "2016-06-24" @default.
• W16228589 creator A5030674279 @default.
• W16228589 creator A5040812294 @default.
• W16228589 date "2005-01-01" @default.
• W16228589 modified "2023-10-18" @default.
• W16228589 title "Posttraumatic epilepsy with special emphasis on prophylaxis and prevention" @default.
• W16228589 cites W1892450427 @default.
• W16228589 cites W1964044359 @default.
• W16228589 cites W1965135994 @default.
• W16228589 cites W1965865373 @default.
• W16228589 cites W1970013882 @default.
• W16228589 cites W1978368438 @default.
• W16228589 cites W1991502382 @default.
• W16228589 cites W1997693301 @default.
• W16228589 cites W2014527486 @default.
• W16228589 cites W2015291504 @default.
• W16228589 cites W2025489907 @default.
• W16228589 cites W2028790213 @default.
• W16228589 cites W2037926670 @default.
• W16228589 cites W2041524723 @default.
• W16228589 cites W2057082715 @default.
• W16228589 cites W2066208071 @default.
• W16228589 cites W2066342851 @default.
• W16228589 cites W2066625990 @default.
• W16228589 cites W2068406659 @default.
• W16228589 cites W2088271493 @default.
• W16228589 cites W2089209433 @default.
• W16228589 cites W2091173699 @default.
• W16228589 cites W2092554796 @default.
• W16228589 cites W2098071052 @default.
• W16228589 cites W2107965006 @default.
• W16228589 cites W2113795277 @default.
• W16228589 cites W2123761065 @default.
• W16228589 cites W2127407670 @default.
• W16228589 cites W2138072888 @default.
• W16228589 cites W2147315535 @default.
• W16228589 cites W2147871959 @default.
• W16228589 cites W2325851205 @default.
• W16228589 cites W2326698703 @default.
• W16228589 cites W2599597499 @default.
• W16228589 cites W2985192072 @default.
• W16228589 cites W4244306633 @default.
• W16228589 cites W4252414228 @default.
• W16228589 doi "https://doi.org/10.1007/3-211-27577-0_3" @default.
• W16228589 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15986723" @default.
• W16228589 hasPublicationYear "2005" @default.
• W16228589 type Work @default.
• W16228589 sameAs 16228589 @default.
• W16228589 citedByCount "35" @default.
• W16228589 countsByYear W162285892013 @default.
• W16228589 countsByYear W162285892014 @default.
• W16228589 countsByYear W162285892015 @default.
• W16228589 countsByYear W162285892016 @default.
• W16228589 countsByYear W162285892017 @default.
• W16228589 countsByYear W162285892019 @default.
• W16228589 countsByYear W162285892020 @default.
• W16228589 countsByYear W162285892021 @default.
• W16228589 countsByYear W162285892022 @default.
• W16228589 crossrefType "book-chapter" @default.
• W16228589 hasAuthorship W16228589A5030674279 @default.
• W16228589 hasAuthorship W16228589A5040812294 @default.
• W16228589 hasConcept C118552586 @default.
• W16228589 hasConcept C141071460 @default.
• W16228589 hasConcept C17744445 @default.
• W16228589 hasConcept C199539241 @default.
• W16228589 hasConcept C2775858608 @default.
• W16228589 hasConcept C2778186239 @default.
• W16228589 hasConcept C2778337148 @default.
• W16228589 hasConcept C2778715236 @default.
• W16228589 hasConcept C2778793413 @default.
• W16228589 hasConcept C2779253243 @default.
• W16228589 hasConcept C2779658751 @default.
• W16228589 hasConcept C42219234 @default.
• W16228589 hasConcept C71924100 @default.
• W16228589 hasConcept C94625758 @default.
• W16228589 hasConcept C98274493 @default.
• W16228589 hasConceptScore W16228589C118552586 @default.
• W16228589 hasConceptScore W16228589C141071460 @default.
• W16228589 hasConceptScore W16228589C17744445 @default.
• W16228589 hasConceptScore W16228589C199539241 @default.
• W16228589 hasConceptScore W16228589C2775858608 @default.
• W16228589 hasConceptScore W16228589C2778186239 @default.
• W16228589 hasConceptScore W16228589C2778337148 @default.
• W16228589 hasConceptScore W16228589C2778715236 @default.
• W16228589 hasConceptScore W16228589C2778793413 @default.
• W16228589 hasConceptScore W16228589C2779253243 @default.
• W16228589 hasConceptScore W16228589C2779658751 @default.
• W16228589 hasConceptScore W16228589C42219234 @default.
• W16228589 hasConceptScore W16228589C71924100 @default.
• W16228589 hasConceptScore W16228589C94625758 @default.
• W16228589 hasConceptScore W16228589C98274493 @default.
• W16228589 hasLocation W162285891 @default.
• W16228589 hasLocation W162285892 @default.
• W16228589 hasOpenAccess W16228589 @default.
• W16228589 hasPrimaryLocation W162285891 @default.
• W16228589 hasRelatedWork W1525117012 @default.
• W16228589 hasRelatedWork W2038315738 @default.

• next