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- W162371135 abstract "B lymphocytes protect individuals against invading pathogens by producing antibody-secreting plasma cells. In this chapter we discuss several fundamental concepts concerning the development, activation, and differentiation of B cells. We consider the role of specific transcription factors in the general development of B cells, the process whereby B cells synthesize receptors for antigen selection processes important for regulating potentially self-reactive B cells and the signals that promote the differentiation of pathogen-specific B cells into antibody-secreting cells. We also discuss several assay systems used to evaluate B cell function, and briefly discuss how toxins might interfere with B cell development and/or function." @default.
- W162371135 created "2016-06-24" @default.
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- W162371135 date "2010-01-01" @default.
- W162371135 modified "2023-09-27" @default.
- W162371135 title "B-Cell Development*" @default.
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- W162371135 doi "https://doi.org/10.1016/b978-0-08-046884-6.00603-5" @default.
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