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- W1624998001 abstract "This chapter focuses on the principle of the instability of the homogeneous state as the source of localization, epigenesis, differentiation, and morphogenesis. This principle is realized in the genes for enzymes of the household intermediary metabolism. These genes constitute a program which is chemically a highly improbable one, and which can arise only through a combination of both natural selection and self-organization. It is transmitted from generation to generation and it is this transmittance that is the only element of preformation in development. This transmitted genetic potential for development has still to be unfolded. This unfolding occurs through the activation of catabolism, which results in an efficient energy metabolism. The conditions for this efficiency are also the conditions for the instability of the homogeneous state in a (cAMP, ATP) reaction-diffusion Turing system. The chapter also focuses on the origin of order and localization in development, but many of the problems considered are fundamental in other areas of biology. Thus the origin of electrical potential differences is central to electrobiology, and the origin of the localized assembly of the cytoskeleton permeates most of biology. The problem of the Cambrian explosion in biological diversity, also considered in this chapter, is the holy grail of evolutionary biology and paleontology." @default.
- W1624998001 created "2016-06-24" @default.
- W1624998001 creator A5068071513 @default.
- W1624998001 date "1994-01-01" @default.
- W1624998001 modified "2023-09-25" @default.
- W1624998001 title "Instability of the Homogeneous State as the Source of Localization, Epigenesis, Differentiation, and Morphogenesis" @default.
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