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• W162544897 abstract "For certain diseases that can only be diagnosed clinically, physicians rely heavily on the presence of disease markers to support or even at times modify their clinical impression. Typically, these markers play an important role in helping to establish a diagnosis and to evaluate the activity of a chronic disease over time. The diagnosis of inflammatory bowel disease (IBD), however, is not based solely on clinical grounds. Invasive endoscopic and radiological as well as histopathological criteria need to be met in order to make a correct diagnosis. The search for a noninvasive diagnostic marker that accurately distinguishes a group of patients with IBD from those unaffected by the disease has become an important focus in IBD research. The challenge lies in finding one marker or a combination thereof, that not only distinguishes IBD from non-IBD, or identifies at risk populations, but can also help clinicians distinguish between the IBD subtypes, ulcerative colitis (UC) or Crohn’s disease (CD). Such diagnostic dilemmas occur as part of every day practice for clinicians caring for children and adults with suspicion of, or a diagnosis of, IBD. Efforts have also been focused on finding ideal evaluative markers that can be used to monitor disease activity and the effect of treatment over time. This search has taken a very exciting turn in the direction of finding markers that can assess the natural history and perhaps predict the course of individual’s disease over time. This chapter highlights the recent advances in the area of IBD markers, discusses the utility and feasibility of these novel markers as well as provides a review of those currently employed in clinical practice." @default.
• W162544897 created "2016-06-24" @default.
• W162544897 creator A5019801327 @default.
• W162544897 creator A5051870878 @default.
• W162544897 date "2003-01-01" @default.
• W162544897 modified "2023-09-23" @default.
• W162544897 title "Inflammatory Bowel Disease Markers" @default.
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