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- W1625794906 abstract "Osteoarthritis (OA) is one of the main causes of disability in the elderly. The consumption of glucosamine is one way to reduce the effects of osteoarthritis, and the global demand for glucosamine is constantly increasing. Thus there is a need to develop production methods which can produce high quality glucosamine in large quantities. The goal of this research was to develop a safe, practical, and efficient glucosamine hydrochloride production method through the use of low-pressure hydrolysis and to analyse the characteristics of the glucosamine produced. The pressurised hydrolysis method used was applied with various combinations of heating time and acid concentration. The extraction used 30 g of chitosan in hydrochloric acid (HCl), with a ratio of 1:9. HCl concentrations were 5%, 8% and 10% with heating times of 30, 60, 90, 120 and 150 minutes at a pressure of 0,5 ATM. The treatment using 5% HCl concentration for 60 minutes produced the best glucosamine hydrochloride. The glucosamine rendement was 65,33%, with 96.33% solubility, a pH of 5,66, LoD of 0,60%, and LoI of 0,23%. The FTIR spectrum absorption pattern showed 99,44% compliance with the standard, proving that the glucosamine hydrolysis was successful." @default.
- W1625794906 created "2016-06-24" @default.
- W1625794906 creator A5036688488 @default.
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- W1625794906 date "2014-10-15" @default.
- W1625794906 modified "2023-09-23" @default.
- W1625794906 title "Development of A Pressurized Hydrolysis Method for Producing Glucosamine" @default.
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- W1625794906 doi "https://doi.org/10.24203/ajafs.v2i5.1641" @default.
- W1625794906 hasPublicationYear "2014" @default.
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