Matches in SemOpenAlex for { <https://semopenalex.org/work/W1626635399> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1626635399 abstract "Neuroprotective agents have the potential to reduce ischemia to penumbra of the cortex, but are time-sensitive. To quickly determine whether a cortical stroke is present without imaging, we created a scoring system based on the NIH stroke scale (NIHSS) that can accurately predict cortical damage in an acute ischemic stroke (AIS).Patients treated with tPA for AIS were retrospectively assessed through prospectively acquired databases at two stroke centers. Stroke was classified as cortical vs. non-cortical stroke. The total NIHSS score, cortical components (gaze, visual fields, language, and neglect) and cortical score (sum of cortical components) were analyzed for site 1 and then validated for site 2 for sensitivity and positive predictive value (PPV) for a cortical stroke.An acute infarct was detected in 194/239 (81%) patients at site 1 and 122/174 (70%) at site 2 on diffusion-weighted MRI. Cortical involvement was found in 71% (site 1) and 75% (site 2). The median cortical score was 25% of the total NIHSS score at both sites. NIHSS ≥ 4 had the highest sensitivity; PPV was 90% for any cortical sign with ≥ 2 points. The best combination of sensitivity and PPV was cortical score/NIHSS score ≥10%.If a trial targeting cortical stroke required that the cortical score represent at least 10% of the total NIHSS score with no imaging, less than 10% of patients with cortical stroke would be missed and less than 18% of patients would be misclassified as having a cortical stroke." @default.
- W1626635399 created "2016-06-24" @default.
- W1626635399 creator A5015408306 @default.
- W1626635399 creator A5020354228 @default.
- W1626635399 creator A5026886390 @default.
- W1626635399 creator A5035161117 @default.
- W1626635399 creator A5039968969 @default.
- W1626635399 creator A5061294013 @default.
- W1626635399 creator A5080030721 @default.
- W1626635399 creator A5084551960 @default.
- W1626635399 date "2013-09-13" @default.
- W1626635399 modified "2023-09-23" @default.
- W1626635399 title "The NIHSS Score and its Components can Predict Cortical Stroke." @default.
- W1626635399 cites W1773516416 @default.
- W1626635399 cites W2003066583 @default.
- W1626635399 cites W2020484901 @default.
- W1626635399 cites W2025211630 @default.
- W1626635399 cites W2042208668 @default.
- W1626635399 cites W2077965065 @default.
- W1626635399 cites W2093072754 @default.
- W1626635399 cites W2124323173 @default.
- W1626635399 cites W2136280619 @default.
- W1626635399 cites W2152685295 @default.
- W1626635399 cites W2269385665 @default.
- W1626635399 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3904284" @default.
- W1626635399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24482782" @default.
- W1626635399 hasPublicationYear "2013" @default.
- W1626635399 type Work @default.
- W1626635399 sameAs 1626635399 @default.
- W1626635399 citedByCount "6" @default.
- W1626635399 countsByYear W16266353992013 @default.
- W1626635399 countsByYear W16266353992015 @default.
- W1626635399 countsByYear W16266353992016 @default.
- W1626635399 countsByYear W16266353992018 @default.
- W1626635399 countsByYear W16266353992020 @default.
- W1626635399 crossrefType "journal-article" @default.
- W1626635399 hasAuthorship W1626635399A5015408306 @default.
- W1626635399 hasAuthorship W1626635399A5020354228 @default.
- W1626635399 hasAuthorship W1626635399A5026886390 @default.
- W1626635399 hasAuthorship W1626635399A5035161117 @default.
- W1626635399 hasAuthorship W1626635399A5039968969 @default.
- W1626635399 hasAuthorship W1626635399A5061294013 @default.
- W1626635399 hasAuthorship W1626635399A5080030721 @default.
- W1626635399 hasAuthorship W1626635399A5084551960 @default.
- W1626635399 hasConcept C126322002 @default.
- W1626635399 hasConcept C127413603 @default.
- W1626635399 hasConcept C164705383 @default.
- W1626635399 hasConcept C1862650 @default.
- W1626635399 hasConcept C2776361831 @default.
- W1626635399 hasConcept C2778818304 @default.
- W1626635399 hasConcept C2780577055 @default.
- W1626635399 hasConcept C2780645631 @default.
- W1626635399 hasConcept C541997718 @default.
- W1626635399 hasConcept C71924100 @default.
- W1626635399 hasConcept C78519656 @default.
- W1626635399 hasConceptScore W1626635399C126322002 @default.
- W1626635399 hasConceptScore W1626635399C127413603 @default.
- W1626635399 hasConceptScore W1626635399C164705383 @default.
- W1626635399 hasConceptScore W1626635399C1862650 @default.
- W1626635399 hasConceptScore W1626635399C2776361831 @default.
- W1626635399 hasConceptScore W1626635399C2778818304 @default.
- W1626635399 hasConceptScore W1626635399C2780577055 @default.
- W1626635399 hasConceptScore W1626635399C2780645631 @default.
- W1626635399 hasConceptScore W1626635399C541997718 @default.
- W1626635399 hasConceptScore W1626635399C71924100 @default.
- W1626635399 hasConceptScore W1626635399C78519656 @default.
- W1626635399 hasLocation W16266353991 @default.
- W1626635399 hasOpenAccess W1626635399 @default.
- W1626635399 hasPrimaryLocation W16266353991 @default.
- W1626635399 hasRelatedWork W1549573233 @default.
- W1626635399 hasRelatedWork W1599639232 @default.
- W1626635399 hasRelatedWork W1600961431 @default.
- W1626635399 hasRelatedWork W1987285391 @default.
- W1626635399 hasRelatedWork W2017223024 @default.
- W1626635399 hasRelatedWork W2052946597 @default.
- W1626635399 hasRelatedWork W2136510344 @default.
- W1626635399 hasRelatedWork W2158657563 @default.
- W1626635399 hasRelatedWork W2256125051 @default.
- W1626635399 hasRelatedWork W2271340923 @default.
- W1626635399 hasRelatedWork W2394959283 @default.
- W1626635399 hasRelatedWork W2516724448 @default.
- W1626635399 hasRelatedWork W2568563371 @default.
- W1626635399 hasRelatedWork W2605320624 @default.
- W1626635399 hasRelatedWork W2731282913 @default.
- W1626635399 hasRelatedWork W2886159279 @default.
- W1626635399 hasRelatedWork W2912186209 @default.
- W1626635399 hasRelatedWork W3030012490 @default.
- W1626635399 hasRelatedWork W3202454775 @default.
- W1626635399 hasRelatedWork W2740200225 @default.
- W1626635399 isParatext "false" @default.
- W1626635399 isRetracted "false" @default.
- W1626635399 magId "1626635399" @default.
- W1626635399 workType "article" @default.