FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W162774078> ?p ?o ?g. }

• W162774078 endingPage "112" @default.
• W162774078 startingPage "37" @default.
• W162774078 abstract "These studies were undertaken to evaluate pulmonary responses of humans sequentially exposed to acidic aerosols and ozone at levels that could reasonably be encountered in actual environmental exposures. Subjects first were exposed to sulfuric acid (H2SO4) aerosol to sensitize the airways to ozone. The exposure protocols were designed to provide more quantitative information about the threshold levels of ozone that produce adverse biological effects and to provide exposure-response data on ozone. Two groups of 30 nonsmoking volunteers of both sexes, between the ages of 18 and 45 years, were recruited. The healthy study population comprised 16 men and 14 women with an average age of 28 years and no airway hyperreactivity. The second group comprised 10 men and 20 women comparable in age to the control group, but with allergic asthma and positive skin tests. The study examined an exposure-response relationship using three levels of ozone ranging from below the current standard to one and one-half times the ambient air quality standard (0.08, 0.12, and 0.18 ppm* [parts per million]) with preexposure 24 hours earlier to H2SO4 (100 micrograms/m3) or sodium chloride (NaCl) (control) aerosol in a 45-m3 environmental chamber. The study used an incomplete block design in which each subject was exposed to four of the six paired experimental atmospheres. Both the selection of paired exposures and the order in which they were presented were randomized. The exposure protocol required nine days: Day 1, training and baseline preexposure measurements; Day 2, the first of the three-hour particle (H2SO4 or NaCl) exposures; Day 3 (24 hours after Day 2), ozone exposure at 0.08, 0.12, or 0.18 ppm for three hours; Day 4 (two to four weeks later), exposure to the same ozone concentration as on Day 4. After at least another two weeks, Days 6, 7, 8, and 9 repeated Days 2, 3, 4, and 5 using a second ozone concentration. All three-hour exposures included several predetermined periods of exercise and pulmonary function measurements. To examine for delayed effects, pulmonary function tests were measured two and four hours after exposure on the ozone days. Data were analyzed over the time course of exposure and by exposure level of ozone at each time point to reveal dose-response relationships more closely. The main findings of the study are as follows. No significant symptomatic or physiologic effects of exposure to either aerosol or ozone on lung function were found for the healthy group.(ABSTRACT TRUNCATED AT 400 WORDS)" @default.
• W162774078 created "2016-06-24" @default.
• W162774078 creator A5024093542 @default.
• W162774078 creator A5026942775 @default.
• W162774078 creator A5026944095 @default.
• W162774078 creator A5031338127 @default.
• W162774078 creator A5038157814 @default.
• W162774078 creator A5055203423 @default.
• W162774078 creator A5061331073 @default.
• W162774078 date "1994-11-01" @default.
• W162774078 modified "2023-09-23" @default.
• W162774078 title "Oxidant and acid aerosol exposure in healthy subjects and subjects with asthma. Part II: Effects of sequential sulfuric acid and ozone exposures on the pulmonary function of healthy subjects and subjects with asthma." @default.
• W162774078 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7848587" @default.
• W162774078 hasPublicationYear "1994" @default.
• W162774078 type Work @default.
• W162774078 sameAs 162774078 @default.
• W162774078 citedByCount "3" @default.
• W162774078 crossrefType "journal-article" @default.
• W162774078 hasAuthorship W162774078A5024093542 @default.
• W162774078 hasAuthorship W162774078A5026942775 @default.
• W162774078 hasAuthorship W162774078A5026944095 @default.
• W162774078 hasAuthorship W162774078A5031338127 @default.
• W162774078 hasAuthorship W162774078A5038157814 @default.
• W162774078 hasAuthorship W162774078A5055203423 @default.
• W162774078 hasAuthorship W162774078A5061331073 @default.
• W162774078 hasConcept C126322002 @default.
• W162774078 hasConcept C178790620 @default.
• W162774078 hasConcept C179104552 @default.
• W162774078 hasConcept C185592680 @default.
• W162774078 hasConcept C2776042228 @default.
• W162774078 hasConcept C2778199549 @default.
• W162774078 hasConcept C2779345167 @default.
• W162774078 hasConcept C2908647359 @default.
• W162774078 hasConcept C33070731 @default.
• W162774078 hasConcept C42407357 @default.
• W162774078 hasConcept C508106653 @default.
• W162774078 hasConcept C71924100 @default.
• W162774078 hasConcept C75603125 @default.
• W162774078 hasConcept C86803240 @default.
• W162774078 hasConcept C99454951 @default.
• W162774078 hasConceptScore W162774078C126322002 @default.
• W162774078 hasConceptScore W162774078C178790620 @default.
• W162774078 hasConceptScore W162774078C179104552 @default.
• W162774078 hasConceptScore W162774078C185592680 @default.
• W162774078 hasConceptScore W162774078C2776042228 @default.
• W162774078 hasConceptScore W162774078C2778199549 @default.
• W162774078 hasConceptScore W162774078C2779345167 @default.
• W162774078 hasConceptScore W162774078C2908647359 @default.
• W162774078 hasConceptScore W162774078C33070731 @default.
• W162774078 hasConceptScore W162774078C42407357 @default.
• W162774078 hasConceptScore W162774078C508106653 @default.
• W162774078 hasConceptScore W162774078C71924100 @default.
• W162774078 hasConceptScore W162774078C75603125 @default.
• W162774078 hasConceptScore W162774078C86803240 @default.
• W162774078 hasConceptScore W162774078C99454951 @default.
• W162774078 hasIssue "70" @default.
• W162774078 hasLocation W1627740781 @default.
• W162774078 hasOpenAccess W162774078 @default.
• W162774078 hasPrimaryLocation W1627740781 @default.
• W162774078 hasRelatedWork W1974068452 @default.
• W162774078 hasRelatedWork W1991955202 @default.
• W162774078 hasRelatedWork W1999974868 @default.
• W162774078 hasRelatedWork W2029884802 @default.
• W162774078 hasRelatedWork W2038378422 @default.
• W162774078 hasRelatedWork W2046681222 @default.
• W162774078 hasRelatedWork W2055164752 @default.
• W162774078 hasRelatedWork W2071257577 @default.
• W162774078 hasRelatedWork W250884749 @default.
• W162774078 hasRelatedWork W1781559957 @default.
• W162774078 isParatext "false" @default.
• W162774078 isRetracted "false" @default.
• W162774078 magId "162774078" @default.
• W162774078 workType "article" @default.