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- W1627883955 abstract "Identifying the neural activity which translates a sensory input into behavioral output isone of the central tasks of neuroscience. The nematode C. elegans serves as a model organismin biology and its connectome of neural connections has been completely mapped.C. elegans are capable of some simple behavior responses to external influences such aschemotaxis and thermotaxis. The responsible neural circuits consisting of sensory neurons,interneurons and motor neurons are subject of recent studies.In this thesis we use an extended Fitzhugh-Nagumo model to study the dynamics of simpleneural circuits. The neurons are coupled via chemical synapses, which can excite andinhibit the post-synaptic neuron. The neurotransmitter-receptor dynamics are governedwith a gating dynamic, which allows for the distinction between fast and slow synapses.In our studies of the neural circuits we find frequency enhancement, chaotic spiking,synchronization of fast and slow firing neurons and periodic bursting. We apply themodel to the temperature sensing circuit of the AWC, AFD and AIY neurons of the C.elegans and reproduce the activity response to temperature change." @default.
- W1627883955 created "2016-06-24" @default.
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- W1627883955 date "2012-08-09" @default.
- W1627883955 modified "2023-09-22" @default.
- W1627883955 title "Case study of an extended Fitzhugh-Nagumo model with chemical synaptic coupling and application to C. elegans functional neural circuits" @default.
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