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- W162821787 abstract "ADYOS BOBBY CHANDRA. Isolation and Characterization of Plantaricin from Lactobacillus plantarum S34 as RNA Helicase Inhibitor Hepatitis C Virus. Research was supervised by HASIM and A. ZAENAL MUSTOPA. The purpose of this study was to isolation and characterization of plantaricin S34 which has inhibition activity against ATPase activity of RNA helicase HCV. Plantaricin was produced by Lactobacillus plantarum S34 isolated from Bekasam, traditional fermentation of meat products from Way Kanan, Lampung. Maximal activity of plantaricin S34 was recorded in MRS broth with 2% glucose 37 °C pH 6,5 after 20 h of growth. Plantaricin S34 results of purification with ammonium sulphate has inhibitory activity of 111,18% (2x dilution). Activity of plantaricin S34 was not affected by 1% SDS, urea, Tween20, Triton X-100, EDTA and 0,1 mg/mL lysozim, catalase, and proteinase-K. The specific activity after purification was 1,49x10 -2 U/mg. The purity of plantaricin S34 increased 18,35 fold than those of the crude protein. According to SDSPAGE, plantaricin S34 is approximately 6,47 kD in size." @default.
- W162821787 created "2016-06-24" @default.
- W162821787 creator A5062069121 @default.
- W162821787 date "2013-01-01" @default.
- W162821787 modified "2023-09-26" @default.
- W162821787 title "Isolasi dan Karakterisasi Plantarisin dari Lactobacillus plantarum S34 sebagai Inhibitor RNA Helikase Virus Hepatitis C" @default.
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