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- W1628575529 abstract "A previous study from this laboratory, using morphological and biochemical (LDH release) parameters, has shown that tungsten carbide-cobalt dust exhibits a greater cytotoxicity toward isolated macrophages than cobalt metal powder alone. The present study extends this comparison by examining additional biological parameters. Glucose uptake and superoxide anion production by isolated macrophages were significantly more depressed by the tungsten carbidecobalt mixture (WC—Co) than by cobalt alone (Co) while pure tungsten carbide (WC) had no effect or even stimulated the cells. For glucose-6-phosphate dehydrogenase and cell-associated plasminogen activator (PA) activities, no difference between Co and WC—Co dusts was observed. These observations add further evidence to our previous findings regarding the different biological reactivity of cobalt metal alone or mixed with tungsten carbide." @default.
- W1628575529 created "2016-06-24" @default.
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- W1628575529 date "1991-10-01" @default.
- W1628575529 modified "2023-09-27" @default.
- W1628575529 title "Biological Responses of Isolated Macrophages to Cobalt Metal and Tungsten Carbide-Cobalt Powders" @default.
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- W1628575529 doi "https://doi.org/10.1111/bcpt.1991.69.4.282" @default.
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