FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1628687528> ?p ?o ?g. }

• W1628687528 endingPage "556" @default.
• W1628687528 startingPage "549" @default.
• W1628687528 abstract "Abstract Mice deficient in complement components C3 (C3 -/-) and C4 (C4 -/-) were found to have a profound defect in their Ab response to a T-dependent Ag (bacteriophage (phi X174). Characterization of the deficient mice demonstrated a diminished level of peanut agglutinin+ germinal centers and a failure in isotype switching despite normal B cell signaling in vitro. The nature of the defect was found to lie at the B cell level, as the T cells were primed in C3- and C4-deficient mice as well as those in wild-type mice. These results, and the finding that the defect could be partly reversed by a 10-fold increase in Ag dose, support the hypothesis that covalent attachment of complement ligands, i.e., C3b and C3d to the Ag-Ab complex, increases its immunogenicity." @default.
• W1628687528 created "2016-06-24" @default.
• W1628687528 creator A5000813097 @default.
• W1628687528 creator A5015792240 @default.
• W1628687528 creator A5018344195 @default.
• W1628687528 creator A5021405467 @default.
• W1628687528 creator A5036370454 @default.
• W1628687528 creator A5046686348 @default.
• W1628687528 creator A5065001474 @default.
• W1628687528 creator A5065891179 @default.
• W1628687528 creator A5068331769 @default.
• W1628687528 creator A5069141856 @default.
• W1628687528 creator A5081180580 @default.
• W1628687528 creator A5085172369 @default.
• W1628687528 creator A5087286759 @default.
• W1628687528 date "1996-07-15" @default.
• W1628687528 modified "2023-10-10" @default.
• W1628687528 title "Regulation of the B cell response to T-dependent antigens by classical pathway complement." @default.
• W1628687528 doi "https://doi.org/10.4049/jimmunol.157.2.549" @default.
• W1628687528 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8752901" @default.
• W1628687528 hasPublicationYear "1996" @default.
• W1628687528 type Work @default.
• W1628687528 sameAs 1628687528 @default.
• W1628687528 citedByCount "276" @default.
• W1628687528 countsByYear W16286875282012 @default.
• W1628687528 countsByYear W16286875282013 @default.
• W1628687528 countsByYear W16286875282014 @default.
• W1628687528 countsByYear W16286875282015 @default.
• W1628687528 countsByYear W16286875282016 @default.
• W1628687528 countsByYear W16286875282017 @default.
• W1628687528 countsByYear W16286875282018 @default.
• W1628687528 countsByYear W16286875282019 @default.
• W1628687528 countsByYear W16286875282020 @default.
• W1628687528 countsByYear W16286875282021 @default.
• W1628687528 countsByYear W16286875282022 @default.
• W1628687528 countsByYear W16286875282023 @default.
• W1628687528 crossrefType "journal-article" @default.
• W1628687528 hasAuthorship W1628687528A5000813097 @default.
• W1628687528 hasAuthorship W1628687528A5015792240 @default.
• W1628687528 hasAuthorship W1628687528A5018344195 @default.
• W1628687528 hasAuthorship W1628687528A5021405467 @default.
• W1628687528 hasAuthorship W1628687528A5036370454 @default.
• W1628687528 hasAuthorship W1628687528A5046686348 @default.
• W1628687528 hasAuthorship W1628687528A5065001474 @default.
• W1628687528 hasAuthorship W1628687528A5065891179 @default.
• W1628687528 hasAuthorship W1628687528A5068331769 @default.
• W1628687528 hasAuthorship W1628687528A5069141856 @default.
• W1628687528 hasAuthorship W1628687528A5081180580 @default.
• W1628687528 hasAuthorship W1628687528A5085172369 @default.
• W1628687528 hasAuthorship W1628687528A5087286759 @default.
• W1628687528 hasBestOaLocation W16286875281 @default.
• W1628687528 hasConcept C111684460 @default.
• W1628687528 hasConcept C137756551 @default.
• W1628687528 hasConcept C147483822 @default.
• W1628687528 hasConcept C153911025 @default.
• W1628687528 hasConcept C159654299 @default.
• W1628687528 hasConcept C175773311 @default.
• W1628687528 hasConcept C185592680 @default.
• W1628687528 hasConcept C189446657 @default.
• W1628687528 hasConcept C202751555 @default.
• W1628687528 hasConcept C203014093 @default.
• W1628687528 hasConcept C2777991845 @default.
• W1628687528 hasConcept C2778453870 @default.
• W1628687528 hasConcept C2780868878 @default.
• W1628687528 hasConcept C542903549 @default.
• W1628687528 hasConcept C55493867 @default.
• W1628687528 hasConcept C86803240 @default.
• W1628687528 hasConcept C95444343 @default.
• W1628687528 hasConcept C96926380 @default.
• W1628687528 hasConceptScore W1628687528C111684460 @default.
• W1628687528 hasConceptScore W1628687528C137756551 @default.
• W1628687528 hasConceptScore W1628687528C147483822 @default.
• W1628687528 hasConceptScore W1628687528C153911025 @default.
• W1628687528 hasConceptScore W1628687528C159654299 @default.
• W1628687528 hasConceptScore W1628687528C175773311 @default.
• W1628687528 hasConceptScore W1628687528C185592680 @default.
• W1628687528 hasConceptScore W1628687528C189446657 @default.
• W1628687528 hasConceptScore W1628687528C202751555 @default.
• W1628687528 hasConceptScore W1628687528C203014093 @default.
• W1628687528 hasConceptScore W1628687528C2777991845 @default.
• W1628687528 hasConceptScore W1628687528C2778453870 @default.
• W1628687528 hasConceptScore W1628687528C2780868878 @default.
• W1628687528 hasConceptScore W1628687528C542903549 @default.
• W1628687528 hasConceptScore W1628687528C55493867 @default.
• W1628687528 hasConceptScore W1628687528C86803240 @default.
• W1628687528 hasConceptScore W1628687528C95444343 @default.
• W1628687528 hasConceptScore W1628687528C96926380 @default.
• W1628687528 hasIssue "2" @default.
• W1628687528 hasLocation W16286875281 @default.
• W1628687528 hasLocation W16286875282 @default.
• W1628687528 hasOpenAccess W1628687528 @default.
• W1628687528 hasPrimaryLocation W16286875281 @default.
• W1628687528 hasRelatedWork W1604776217 @default.
• W1628687528 hasRelatedWork W1803508310 @default.
• W1628687528 hasRelatedWork W1837294723 @default.
• W1628687528 hasRelatedWork W2003685447 @default.
• W1628687528 hasRelatedWork W2075634030 @default.
• W1628687528 hasRelatedWork W2965090569 @default.

• next