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- W163030544 abstract "Abstract The antiphospholipid syndrome (APS) is defined by the occurrence of venous and arterial thromboses, often multiple, and pregnancy morbidity, in the presence of antiphospholipid antibodies, namely lupus anticoagulant, anticardiolipin antibodies, or anti-β2glycoprotein I antibodies. The APS can be found in patients having neither clinical nor laboratory evidence of another definable condition (primary APS) or it may be associated with other diseases, mainly systemic lupus erythematosus, but occasionally with other autoimmune conditions, infections, drugs and malignancies. Rapid chronological occlusive events, occurring over days to weeks, have been termed the catastrophic APS. Other postulated APS subsets include the microangiopathic and the seronegative APS. In this chapter, we will review the main historical events related with the discovery and characterization of this syndrome as well as the efforts to classify and subdivide its wide spectrum of presentations." @default.
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- W163030544 date "2009-01-01" @default.
- W163030544 modified "2023-09-26" @default.
- W163030544 title "Chapter 1 History, Classification, and Subsets of the Antiphospholipid Syndrome" @default.
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- W163030544 doi "https://doi.org/10.1016/s1571-5078(08)00401-7" @default.
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