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- W1630980474 abstract "The chapter helps to choose the appropriate inhibitor when part of or the whole electron-transfer chain of the bc1 complex is to be blocked, independent of whether single-turnover or steady-state experiments are to be performed. The chapter focuses on a classification of the various inhibitors into definite groups, in accordance with their point of action. The inhibitors are discussed using the model of the bc1 complex. A multitude of inhibitors is available that can be classified into three groups: various β-methoxyacrylates (group I); hydroxyquinone analogs (group II); and antimycin, funiculosin, and certain quinone analogs (group III). A fourth group–the chromone inhibitors (stigmatellins) have also been discovered. They completely block the Qo center, but show binding properties different to both group I and group II inhibitors. The structural data and the physicochemical data of the different molecules are compiled." @default.
- W1630980474 created "2016-06-24" @default.
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- W1630980474 date "1986-01-01" @default.
- W1630980474 modified "2023-10-01" @default.
- W1630980474 title "[24] Use of specific inhibitors on the mitochondrial bc1 complex" @default.
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- W1630980474 doi "https://doi.org/10.1016/s0076-6879(86)26026-7" @default.
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