Matches in SemOpenAlex for { <https://semopenalex.org/work/W1632515834> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1632515834 endingPage "2659" @default.
- W1632515834 startingPage "2653" @default.
- W1632515834 abstract "The potential role of calcium as a regulator of goblet cell differentiation was tested by culturing duodenal explants from 14-day chicken embryos in media containing a range of calcium concentrations. Extracellular calcium in vitro approximated the range of plasma calcium concentration that was found to rise by 16% during the third week of embryonic development. As ionic calcium was increased from 0.9 to 2.0 mM in 48-h cultures, the number of goblet cells per 100 ridges increased progressively from 29 +/- 2.2 to 158 +/- 6.9 while attaining a distribution on the previllous ridges similar to that in ovo. The rate of goblet cell differentiation in vitro exceeded that in ovo when extracellular calcium was increased to 1.1 mM and was maximal at 1.6-2.0 mM calcium. Neither the growth of previllous ridges nor gross morphology of the tissue was altered as extracellular calcium was increased. Goblet cell differentiation in 1.3 mM calcium was stimulated by 0.1 microM calcium ionophore and inhibited by the calmodulin antagonist trifluoperazine, indicating an intracellular site for calcium action. These results indicate that calcium plays a primary role in regulating goblet cell differentiation in embryonic intestine and suggest that rising levels of plasma calcium influence the rate of differentiation in ovo." @default.
- W1632515834 created "2016-06-24" @default.
- W1632515834 creator A5034415681 @default.
- W1632515834 creator A5044242203 @default.
- W1632515834 date "1989-12-01" @default.
- W1632515834 modified "2023-09-26" @default.
- W1632515834 title "Regulation of goblet cell differentiation by calcium in embryonic chick intestine" @default.
- W1632515834 cites W153187251 @default.
- W1632515834 cites W1969928750 @default.
- W1632515834 cites W1979555576 @default.
- W1632515834 cites W1983150970 @default.
- W1632515834 cites W2002405771 @default.
- W1632515834 cites W2012960732 @default.
- W1632515834 cites W2023649138 @default.
- W1632515834 cites W2023651939 @default.
- W1632515834 cites W2023896274 @default.
- W1632515834 cites W2029785826 @default.
- W1632515834 cites W2034654703 @default.
- W1632515834 cites W2038085058 @default.
- W1632515834 cites W2038576163 @default.
- W1632515834 cites W2060481305 @default.
- W1632515834 cites W2102788552 @default.
- W1632515834 cites W819682860 @default.
- W1632515834 doi "https://doi.org/10.1096/fasebj.3.14.2512193" @default.
- W1632515834 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2512193" @default.
- W1632515834 hasPublicationYear "1989" @default.
- W1632515834 type Work @default.
- W1632515834 sameAs 1632515834 @default.
- W1632515834 citedByCount "29" @default.
- W1632515834 countsByYear W16325158342013 @default.
- W1632515834 crossrefType "journal-article" @default.
- W1632515834 hasAuthorship W1632515834A5034415681 @default.
- W1632515834 hasAuthorship W1632515834A5044242203 @default.
- W1632515834 hasConcept C104317684 @default.
- W1632515834 hasConcept C134018914 @default.
- W1632515834 hasConcept C148738053 @default.
- W1632515834 hasConcept C178790620 @default.
- W1632515834 hasConcept C181080969 @default.
- W1632515834 hasConcept C185592680 @default.
- W1632515834 hasConcept C196843134 @default.
- W1632515834 hasConcept C2778765379 @default.
- W1632515834 hasConcept C28406088 @default.
- W1632515834 hasConcept C519063684 @default.
- W1632515834 hasConcept C55493867 @default.
- W1632515834 hasConcept C86803240 @default.
- W1632515834 hasConcept C87073359 @default.
- W1632515834 hasConcept C95444343 @default.
- W1632515834 hasConceptScore W1632515834C104317684 @default.
- W1632515834 hasConceptScore W1632515834C134018914 @default.
- W1632515834 hasConceptScore W1632515834C148738053 @default.
- W1632515834 hasConceptScore W1632515834C178790620 @default.
- W1632515834 hasConceptScore W1632515834C181080969 @default.
- W1632515834 hasConceptScore W1632515834C185592680 @default.
- W1632515834 hasConceptScore W1632515834C196843134 @default.
- W1632515834 hasConceptScore W1632515834C2778765379 @default.
- W1632515834 hasConceptScore W1632515834C28406088 @default.
- W1632515834 hasConceptScore W1632515834C519063684 @default.
- W1632515834 hasConceptScore W1632515834C55493867 @default.
- W1632515834 hasConceptScore W1632515834C86803240 @default.
- W1632515834 hasConceptScore W1632515834C87073359 @default.
- W1632515834 hasConceptScore W1632515834C95444343 @default.
- W1632515834 hasIssue "14" @default.
- W1632515834 hasLocation W16325158341 @default.
- W1632515834 hasLocation W16325158342 @default.
- W1632515834 hasOpenAccess W1632515834 @default.
- W1632515834 hasPrimaryLocation W16325158341 @default.
- W1632515834 hasRelatedWork W1983700788 @default.
- W1632515834 hasRelatedWork W1988480300 @default.
- W1632515834 hasRelatedWork W2043421191 @default.
- W1632515834 hasRelatedWork W2060962205 @default.
- W1632515834 hasRelatedWork W2072606396 @default.
- W1632515834 hasRelatedWork W2079441621 @default.
- W1632515834 hasRelatedWork W2362310773 @default.
- W1632515834 hasRelatedWork W2379190341 @default.
- W1632515834 hasRelatedWork W2404073374 @default.
- W1632515834 hasRelatedWork W2411134315 @default.
- W1632515834 hasVolume "3" @default.
- W1632515834 isParatext "false" @default.
- W1632515834 isRetracted "false" @default.
- W1632515834 magId "1632515834" @default.
- W1632515834 workType "article" @default.