FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1634111167> ?p ?o ?g. }

• W1634111167 endingPage "449" @default.
• W1634111167 startingPage "449" @default.
• W1634111167 abstract "Pharmacognosy Magazine,2015,11,43,449-454.DOI:10.4103/0973-1296.160447Published:July 2015Type:Original ArticleAuthors:Yusi Zhang, Ting Lv, Min Li, Ting Xue, Hui Liu, Weiming Zhang, Xiaoyu Ding, and Ziheng Zhuang Author(s) affiliations:Yusi Zhang1, Ting Lv1, Min Li2, Ting Xue2, Hui Liu2, Weiming Zhang1, Xiaoyu Ding1, Ziheng Zhuang1 1 College of Life Sciences, Nanjing Normal University, Nanjing, 210046, China 2 School of Pharmaceutical Engineering and Life Sciences, Changzhou University, Changzhou, 213164, China Abstract:Background: Polysaccharide isolated from Bletilla striata, a well known traditional Chinese medicine (Bletilla striata polysaccharide [BSP]) has been found to play important roles in endothelial cells proliferation, inducible nitric oxide stimulation, wound healing acceleration and other processes. Recent studies found that B. striata has anti oxidative properties, however, potential anti aging effects of BSP in whole organisms has not been characterized. Objective: To investigate whether BSP has anti aging effects on Caenorhabditis elegans. Materials and Methods: After treatment with BSP, the lifespan, locomotion ability, and stress resistance of C. elegans was determined. To provide insight into the underlying mechanism for the anti aging effect of BSP, we measured its effect on bacterial growth, brood size of C. elegans, and the insulin/insulin like growth factor (IGF) signaling pathway. Results: After BSP treatment, the lifespan of C. elegans was extended, and its locomotion ability and stress resistance were increased. BSP was found to have no effect on bacterial growth or on reproduction of C. elegans, However, mRNA levels of age-1 and hcf-1 were reduced after BSP treatment. Additionally, we observed that BSP did not extend the lifespan of daf 16 mutant animals. Conclusion: BSP produces an anti aging effect on C. elegans through the insulin/IGF signaling pathway and holds promise for future development as a functional food. Keywords:Anti-aging, Bletilla striata polysaccharide, Caenorhabditis elegans, lifespan, stress resistanceView:PDF (1.47 MB) Full Text" @default.
• W1634111167 created "2016-06-24" @default.
• W1634111167 creator A5014963018 @default.
• W1634111167 creator A5018711013 @default.
• W1634111167 creator A5059605597 @default.
• W1634111167 creator A5073469082 @default.
• W1634111167 creator A5074107710 @default.
• W1634111167 creator A5080031001 @default.
• W1634111167 creator A5083950830 @default.
• W1634111167 creator A5089508326 @default.
• W1634111167 date "2015-01-01" @default.
• W1634111167 modified "2023-10-14" @default.
• W1634111167 title "Anti-aging effect of polysaccharide from Bletilla striata on nematode Caenorhabditis elegans" @default.
• W1634111167 cites W1619158228 @default.
• W1634111167 cites W1970981335 @default.
• W1634111167 cites W1983065003 @default.
• W1634111167 cites W1985647060 @default.
• W1634111167 cites W1988776142 @default.
• W1634111167 cites W1990185604 @default.
• W1634111167 cites W2001302985 @default.
• W1634111167 cites W2005029264 @default.
• W1634111167 cites W2026533340 @default.
• W1634111167 cites W2034139987 @default.
• W1634111167 cites W2042926714 @default.
• W1634111167 cites W2047292976 @default.
• W1634111167 cites W2054339063 @default.
• W1634111167 cites W2058484936 @default.
• W1634111167 cites W2059080632 @default.
• W1634111167 cites W2072309486 @default.
• W1634111167 cites W2080349795 @default.
• W1634111167 cites W2093935763 @default.
• W1634111167 cites W2096185853 @default.
• W1634111167 cites W2106128801 @default.
• W1634111167 cites W2106204747 @default.
• W1634111167 cites W2115708583 @default.
• W1634111167 cites W2132716318 @default.
• W1634111167 cites W2136870925 @default.
• W1634111167 cites W2148887342 @default.
• W1634111167 cites W2149863676 @default.
• W1634111167 cites W2164150572 @default.
• W1634111167 cites W94412592 @default.
• W1634111167 doi "https://doi.org/10.4103/0973-1296.160447" @default.
• W1634111167 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4522829" @default.
• W1634111167 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26246718" @default.
• W1634111167 hasPublicationYear "2015" @default.
• W1634111167 type Work @default.
• W1634111167 sameAs 1634111167 @default.
• W1634111167 citedByCount "46" @default.
• W1634111167 countsByYear W16341111672016 @default.
• W1634111167 countsByYear W16341111672017 @default.
• W1634111167 countsByYear W16341111672018 @default.
• W1634111167 countsByYear W16341111672019 @default.
• W1634111167 countsByYear W16341111672020 @default.
• W1634111167 countsByYear W16341111672021 @default.
• W1634111167 countsByYear W16341111672022 @default.
• W1634111167 countsByYear W16341111672023 @default.
• W1634111167 crossrefType "journal-article" @default.
• W1634111167 hasAuthorship W1634111167A5014963018 @default.
• W1634111167 hasAuthorship W1634111167A5018711013 @default.
• W1634111167 hasAuthorship W1634111167A5059605597 @default.
• W1634111167 hasAuthorship W1634111167A5073469082 @default.
• W1634111167 hasAuthorship W1634111167A5074107710 @default.
• W1634111167 hasAuthorship W1634111167A5080031001 @default.
• W1634111167 hasAuthorship W1634111167A5083950830 @default.
• W1634111167 hasAuthorship W1634111167A5089508326 @default.
• W1634111167 hasBestOaLocation W16341111672 @default.
• W1634111167 hasConcept C104317684 @default.
• W1634111167 hasConcept C134018914 @default.
• W1634111167 hasConcept C2776496032 @default.
• W1634111167 hasConcept C2778944004 @default.
• W1634111167 hasConcept C519581460 @default.
• W1634111167 hasConcept C54355233 @default.
• W1634111167 hasConcept C556039675 @default.
• W1634111167 hasConcept C71924100 @default.
• W1634111167 hasConcept C86803240 @default.
• W1634111167 hasConcept C98274493 @default.
• W1634111167 hasConceptScore W1634111167C104317684 @default.
• W1634111167 hasConceptScore W1634111167C134018914 @default.
• W1634111167 hasConceptScore W1634111167C2776496032 @default.
• W1634111167 hasConceptScore W1634111167C2778944004 @default.
• W1634111167 hasConceptScore W1634111167C519581460 @default.
• W1634111167 hasConceptScore W1634111167C54355233 @default.
• W1634111167 hasConceptScore W1634111167C556039675 @default.
• W1634111167 hasConceptScore W1634111167C71924100 @default.
• W1634111167 hasConceptScore W1634111167C86803240 @default.
• W1634111167 hasConceptScore W1634111167C98274493 @default.
• W1634111167 hasIssue "43" @default.
• W1634111167 hasLocation W16341111671 @default.
• W1634111167 hasLocation W16341111672 @default.
• W1634111167 hasLocation W16341111673 @default.
• W1634111167 hasLocation W16341111674 @default.
• W1634111167 hasOpenAccess W1634111167 @default.
• W1634111167 hasPrimaryLocation W16341111671 @default.
• W1634111167 hasRelatedWork W2079040627 @default.
• W1634111167 hasRelatedWork W2107933066 @default.
• W1634111167 hasRelatedWork W2145924285 @default.
• W1634111167 hasRelatedWork W2276115873 @default.
• W1634111167 hasRelatedWork W2345399109 @default.

• next