FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1635037663> ?p ?o ?g. }

• W1635037663 endingPage "188" @default.
• W1635037663 startingPage "182" @default.
• W1635037663 abstract "Traumatic brain injury (TBI) is a major cause of disability. Depression is one of the major squeal of TBI in both in-patient and out-patient populations. Depression is associated with numerous negative outcomes, thus affecting quality-of-life (QOL) adversely in these patients. Addressing depression in treatment regimen of TBI may improve QOL of these patients.The present study is designed to evaluate the role of sertraline in post TBI depression and its impact on QOL.Eighty male patients with post TBI depression were included in the study among the 250 male patients of mild to moderate TBI recruited for the evaluation. Half of the patients were given sertraline 50 mg PO, whereas other half served as control without sertraline treatment. Participants were assessed on Glasgow Coma scale, Patient Health Questionnaire-9 (PHQ-9) and World Health Organization QOL (WHOQOL) at regular interval till the end of 6 months.Depression was found in 35.6% of total patients recruited. Most of the patients (63.1%) were below 35 years of age. Depression was more common in mild TBI cases than those with moderate TBI (53.7% vs. 46.25%, P = 0.04). Left side brain injury (56.25%) with cerebral contusions was more commonly associated with depression (P = 0.04). Patients in sertraline group responded well to treatment with significant improvement in mod symptoms (PHQ-9 score 14.88 ± 3.603 vs. 5.33 ± 2.98, P = 0.04)). All the four domains of QOL improved significantly in sertraline group than the control group with sertraline treatment.Management of TBI should also focus on treatment of associated mood symptoms, which is likely to be associated with poor QOL in these patients. Sertraline has been found to be effective in the treatment of depression with significant improvement in QOL in TBI patients." @default.
• W1635037663 created "2016-06-24" @default.
• W1635037663 creator A5001436536 @default.
• W1635037663 creator A5030873899 @default.
• W1635037663 creator A5034216874 @default.
• W1635037663 creator A5035091200 @default.
• W1635037663 creator A5073245143 @default.
• W1635037663 date "2014-12-01" @default.
• W1635037663 modified "2023-10-02" @default.
• W1635037663 title "Role of sertraline in posttraumatic brain injury depression and quality-of-life in TBI" @default.
• W1635037663 cites W1114907 @default.
• W1635037663 cites W1546472035 @default.
• W1635037663 cites W1569179950 @default.
• W1635037663 cites W1603121691 @default.
• W1635037663 cites W1707893729 @default.
• W1635037663 cites W1738386920 @default.
• W1635037663 cites W189298821 @default.
• W1635037663 cites W1970159591 @default.
• W1635037663 cites W1979081415 @default.
• W1635037663 cites W1984135336 @default.
• W1635037663 cites W1990514899 @default.
• W1635037663 cites W2029113867 @default.
• W1635037663 cites W2054974318 @default.
• W1635037663 cites W2055505621 @default.
• W1635037663 cites W2056884334 @default.
• W1635037663 cites W2062425882 @default.
• W1635037663 cites W2066330017 @default.
• W1635037663 cites W2071987065 @default.
• W1635037663 cites W2080791253 @default.
• W1635037663 cites W2094943913 @default.
• W1635037663 cites W2109935313 @default.
• W1635037663 cites W2111474478 @default.
• W1635037663 cites W2118974951 @default.
• W1635037663 cites W2132322340 @default.
• W1635037663 cites W2145062984 @default.
• W1635037663 cites W2146599657 @default.
• W1635037663 cites W2154174081 @default.
• W1635037663 cites W2177735101 @default.
• W1635037663 cites W2327963359 @default.
• W1635037663 cites W2406697481 @default.
• W1635037663 cites W2742689 @default.
• W1635037663 doi "https://doi.org/10.4103/1793-5482.146597" @default.
• W1635037663 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4323960" @default.
• W1635037663 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25685213" @default.
• W1635037663 hasPublicationYear "2014" @default.
• W1635037663 type Work @default.
• W1635037663 sameAs 1635037663 @default.
• W1635037663 citedByCount "17" @default.
• W1635037663 countsByYear W16350376632016 @default.
• W1635037663 countsByYear W16350376632017 @default.
• W1635037663 countsByYear W16350376632018 @default.
• W1635037663 countsByYear W16350376632019 @default.
• W1635037663 countsByYear W16350376632020 @default.
• W1635037663 countsByYear W16350376632021 @default.
• W1635037663 countsByYear W16350376632022 @default.
• W1635037663 crossrefType "journal-article" @default.
• W1635037663 hasAuthorship W1635037663A5001436536 @default.
• W1635037663 hasAuthorship W1635037663A5030873899 @default.
• W1635037663 hasAuthorship W1635037663A5034216874 @default.
• W1635037663 hasAuthorship W1635037663A5035091200 @default.
• W1635037663 hasAuthorship W1635037663A5073245143 @default.
• W1635037663 hasBestOaLocation W16350376631 @default.
• W1635037663 hasConcept C118552586 @default.
• W1635037663 hasConcept C126322002 @default.
• W1635037663 hasConcept C139719470 @default.
• W1635037663 hasConcept C159110408 @default.
• W1635037663 hasConcept C162324750 @default.
• W1635037663 hasConcept C17624336 @default.
• W1635037663 hasConcept C1862650 @default.
• W1635037663 hasConcept C2776867660 @default.
• W1635037663 hasConcept C2777669559 @default.
• W1635037663 hasConcept C2778529449 @default.
• W1635037663 hasConcept C2779177272 @default.
• W1635037663 hasConcept C2779951463 @default.
• W1635037663 hasConcept C2781017439 @default.
• W1635037663 hasConcept C2781161787 @default.
• W1635037663 hasConcept C2781413609 @default.
• W1635037663 hasConcept C3019858935 @default.
• W1635037663 hasConcept C558461103 @default.
• W1635037663 hasConcept C71924100 @default.
• W1635037663 hasConceptScore W1635037663C118552586 @default.
• W1635037663 hasConceptScore W1635037663C126322002 @default.
• W1635037663 hasConceptScore W1635037663C139719470 @default.
• W1635037663 hasConceptScore W1635037663C159110408 @default.
• W1635037663 hasConceptScore W1635037663C162324750 @default.
• W1635037663 hasConceptScore W1635037663C17624336 @default.
• W1635037663 hasConceptScore W1635037663C1862650 @default.
• W1635037663 hasConceptScore W1635037663C2776867660 @default.
• W1635037663 hasConceptScore W1635037663C2777669559 @default.
• W1635037663 hasConceptScore W1635037663C2778529449 @default.
• W1635037663 hasConceptScore W1635037663C2779177272 @default.
• W1635037663 hasConceptScore W1635037663C2779951463 @default.
• W1635037663 hasConceptScore W1635037663C2781017439 @default.
• W1635037663 hasConceptScore W1635037663C2781161787 @default.
• W1635037663 hasConceptScore W1635037663C2781413609 @default.
• W1635037663 hasConceptScore W1635037663C3019858935 @default.
• W1635037663 hasConceptScore W1635037663C558461103 @default.
• W1635037663 hasConceptScore W1635037663C71924100 @default.

• next