FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W163561699> ?p ?o ?g. }

• W163561699 endingPage "1090" @default.
• W163561699 startingPage "1084" @default.
• W163561699 abstract "A member of a new subclass of the voltage-activated sodium channel genes has been cloned from the human medullary thyroid carcinoma (hMTC) cell line. The cDNA of hNE-Na (human neuroendocrine sodium channel) encodes a 1977 amino acid protein which phylogenetically represents a link between sodium channels isolated from skeletal muscle and brain. The hNE-Na alpha subunit was transiently expressed in human embryonic kidney cells either alone or in combination with the human sodium channel beta 1 subunit. The channel exhibited rapid activation and inactivation kinetics, and was blocked by tetrodotoxin and cadmium with IC50 values of 24.5 nM and 1.1 mM, respectively. Action potentials were generated in cells expressing high levels of hNE-Na. Northern blot and reverse transcription-polymerase chain reaction (RT-PCR) analyses demonstrated its expression in hMTC cells, in a C-cell carcinoma, and in thyroid and adrenal gland. Transcripts were not identified in pituitary gland, brain, heart, liver or kidney, indicating that the hNE-Na is a sodium channel solely expressed in neuroendocrine cells." @default.
• W163561699 created "2016-06-24" @default.
• W163561699 creator A5016660545 @default.
• W163561699 creator A5056752653 @default.
• W163561699 creator A5075670973 @default.
• W163561699 creator A5091874127 @default.
• W163561699 date "1995-03-01" @default.
• W163561699 modified "2023-10-14" @default.
• W163561699 title "Structure and functional expression of a new member of the tetrodotoxin-sensitive voltage-activated sodium channel family from human neuroendocrine cells." @default.
• W163561699 cites W1964606508 @default.
• W163561699 cites W1985146688 @default.
• W163561699 cites W1997436303 @default.
• W163561699 cites W2003255866 @default.
• W163561699 cites W2027085605 @default.
• W163561699 cites W2037384321 @default.
• W163561699 cites W2042036078 @default.
• W163561699 cites W2067995523 @default.
• W163561699 cites W2068684319 @default.
• W163561699 cites W2069079626 @default.
• W163561699 cites W2080823382 @default.
• W163561699 cites W2081880350 @default.
• W163561699 cites W2083978369 @default.
• W163561699 cites W2093297294 @default.
• W163561699 cites W2094193659 @default.
• W163561699 cites W2094362927 @default.
• W163561699 cites W2132146004 @default.
• W163561699 cites W2138757225 @default.
• W163561699 cites W2141344931 @default.
• W163561699 cites W2149208773 @default.
• W163561699 cites W2155985861 @default.
• W163561699 cites W2169459792 @default.
• W163561699 cites W2410635702 @default.
• W163561699 cites W2435854223 @default.
• W163561699 cites W54507635 @default.
• W163561699 doi "https://doi.org/10.1002/j.1460-2075.1995.tb07091.x" @default.
• W163561699 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/398185" @default.
• W163561699 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7720699" @default.
• W163561699 hasPublicationYear "1995" @default.
• W163561699 type Work @default.
• W163561699 sameAs 163561699 @default.
• W163561699 citedByCount "295" @default.
• W163561699 countsByYear W1635616992012 @default.
• W163561699 countsByYear W1635616992013 @default.
• W163561699 countsByYear W1635616992014 @default.
• W163561699 countsByYear W1635616992015 @default.
• W163561699 countsByYear W1635616992016 @default.
• W163561699 countsByYear W1635616992017 @default.
• W163561699 countsByYear W1635616992018 @default.
• W163561699 countsByYear W1635616992019 @default.
• W163561699 countsByYear W1635616992020 @default.
• W163561699 countsByYear W1635616992021 @default.
• W163561699 countsByYear W1635616992022 @default.
• W163561699 countsByYear W1635616992023 @default.
• W163561699 crossrefType "journal-article" @default.
• W163561699 hasAuthorship W163561699A5016660545 @default.
• W163561699 hasAuthorship W163561699A5056752653 @default.
• W163561699 hasAuthorship W163561699A5075670973 @default.
• W163561699 hasAuthorship W163561699A5091874127 @default.
• W163561699 hasBestOaLocation W1635616991 @default.
• W163561699 hasConcept C104292427 @default.
• W163561699 hasConcept C104317684 @default.
• W163561699 hasConcept C126322002 @default.
• W163561699 hasConcept C134018914 @default.
• W163561699 hasConcept C153911025 @default.
• W163561699 hasConcept C178790620 @default.
• W163561699 hasConcept C185592680 @default.
• W163561699 hasConcept C2776741303 @default.
• W163561699 hasConcept C2776986425 @default.
• W163561699 hasConcept C50952357 @default.
• W163561699 hasConcept C537181965 @default.
• W163561699 hasConcept C55493867 @default.
• W163561699 hasConcept C71924100 @default.
• W163561699 hasConcept C83730767 @default.
• W163561699 hasConcept C86803240 @default.
• W163561699 hasConceptScore W163561699C104292427 @default.
• W163561699 hasConceptScore W163561699C104317684 @default.
• W163561699 hasConceptScore W163561699C126322002 @default.
• W163561699 hasConceptScore W163561699C134018914 @default.
• W163561699 hasConceptScore W163561699C153911025 @default.
• W163561699 hasConceptScore W163561699C178790620 @default.
• W163561699 hasConceptScore W163561699C185592680 @default.
• W163561699 hasConceptScore W163561699C2776741303 @default.
• W163561699 hasConceptScore W163561699C2776986425 @default.
• W163561699 hasConceptScore W163561699C50952357 @default.
• W163561699 hasConceptScore W163561699C537181965 @default.
• W163561699 hasConceptScore W163561699C55493867 @default.
• W163561699 hasConceptScore W163561699C71924100 @default.
• W163561699 hasConceptScore W163561699C83730767 @default.
• W163561699 hasConceptScore W163561699C86803240 @default.
• W163561699 hasIssue "6" @default.
• W163561699 hasLocation W1635616991 @default.
• W163561699 hasLocation W1635616992 @default.
• W163561699 hasLocation W1635616993 @default.
• W163561699 hasOpenAccess W163561699 @default.
• W163561699 hasPrimaryLocation W1635616991 @default.
• W163561699 hasRelatedWork W1968530210 @default.
• W163561699 hasRelatedWork W2025660850 @default.
• W163561699 hasRelatedWork W2032059291 @default.

• next