FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W163567197> ?p ?o ?g. }

• W163567197 endingPage "91" @default.
• W163567197 startingPage "1585" @default.
• W163567197 abstract "Since chondrosarcoma has a high resistance to conventional chemotherapy and radiotherapy, surgical resection is currently the only effective treatment. Histone deacetylase (HDAC) inhibitor exert anticancer effects, but have not been tested in chondrosarcoma.We investigated the phenotypic change in chondrosarcoma cells treated with SAHA by cell viability assay, Western blot, flow cytometric analysis and electron microscopy.SAHA inhibited the growth of chondrosarcoma cell lines and induced apoptosis in SW1353 with a cleaved-PARP expression and sub-G1 fragmentation according to flow cytometric analysis. On the other hand, in RCS and OUMS-27, SAHA induced autophagy-associated cell death as shown by the detection of autophagosome-specific protein and specific ultrastructural morphology in the cytoplasm. In addition, SAHA significantly inhibited tumor growth in an in vivo xenograft model.These results suggest that SAHA might be a promising agent for performing clinically useful chemotherapy against chondrosarcomas." @default.
• W163567197 created "2016-06-24" @default.
• W163567197 creator A5011966088 @default.
• W163567197 creator A5016818840 @default.
• W163567197 creator A5022274058 @default.
• W163567197 creator A5029431318 @default.
• W163567197 creator A5031069594 @default.
• W163567197 creator A5046604918 @default.
• W163567197 creator A5075584203 @default.
• W163567197 creator A5080130611 @default.
• W163567197 creator A5091776300 @default.
• W163567197 date "2008-07-18" @default.
• W163567197 modified "2023-09-23" @default.
• W163567197 title "Suberoylanilide hydroxamic acid (SAHA) induces apoptosis or autophagy-associated cell death in chondrosarcoma cell lines." @default.
• W163567197 cites W1481633630 @default.
• W163567197 cites W1563624749 @default.
• W163567197 cites W1567485746 @default.
• W163567197 cites W1920958927 @default.
• W163567197 cites W1965072143 @default.
• W163567197 cites W1977767269 @default.
• W163567197 cites W2004312713 @default.
• W163567197 cites W2008963728 @default.
• W163567197 cites W2009944379 @default.
• W163567197 cites W2012337697 @default.
• W163567197 cites W2030822086 @default.
• W163567197 cites W2032025865 @default.
• W163567197 cites W2040901619 @default.
• W163567197 cites W2070706779 @default.
• W163567197 cites W2078331902 @default.
• W163567197 cites W2108086395 @default.
• W163567197 cites W2123245958 @default.
• W163567197 cites W2135619784 @default.
• W163567197 cites W2135636594 @default.
• W163567197 cites W2156320420 @default.
• W163567197 cites W2163962374 @default.
• W163567197 cites W2164382188 @default.
• W163567197 cites W2313004864 @default.
• W163567197 cites W2345727187 @default.
• W163567197 cites W2411667254 @default.
• W163567197 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18630516" @default.
• W163567197 hasPublicationYear "2008" @default.
• W163567197 type Work @default.
• W163567197 sameAs 163567197 @default.
• W163567197 citedByCount "38" @default.
• W163567197 countsByYear W1635671972012 @default.
• W163567197 countsByYear W1635671972013 @default.
• W163567197 countsByYear W1635671972014 @default.
• W163567197 countsByYear W1635671972015 @default.
• W163567197 countsByYear W1635671972016 @default.
• W163567197 countsByYear W1635671972017 @default.
• W163567197 countsByYear W1635671972018 @default.
• W163567197 countsByYear W1635671972019 @default.
• W163567197 countsByYear W1635671972021 @default.
• W163567197 countsByYear W1635671972022 @default.
• W163567197 crossrefType "journal-article" @default.
• W163567197 hasAuthorship W163567197A5011966088 @default.
• W163567197 hasAuthorship W163567197A5016818840 @default.
• W163567197 hasAuthorship W163567197A5022274058 @default.
• W163567197 hasAuthorship W163567197A5029431318 @default.
• W163567197 hasAuthorship W163567197A5031069594 @default.
• W163567197 hasAuthorship W163567197A5046604918 @default.
• W163567197 hasAuthorship W163567197A5075584203 @default.
• W163567197 hasAuthorship W163567197A5080130611 @default.
• W163567197 hasAuthorship W163567197A5091776300 @default.
• W163567197 hasConcept C104317684 @default.
• W163567197 hasConcept C142724271 @default.
• W163567197 hasConcept C185592680 @default.
• W163567197 hasConcept C190283241 @default.
• W163567197 hasConcept C203522944 @default.
• W163567197 hasConcept C2776262904 @default.
• W163567197 hasConcept C2776302905 @default.
• W163567197 hasConcept C2776694085 @default.
• W163567197 hasConcept C2778305200 @default.
• W163567197 hasConcept C31573885 @default.
• W163567197 hasConcept C502942594 @default.
• W163567197 hasConcept C54355233 @default.
• W163567197 hasConcept C55493867 @default.
• W163567197 hasConcept C62112901 @default.
• W163567197 hasConcept C64927066 @default.
• W163567197 hasConcept C71924100 @default.
• W163567197 hasConcept C81885089 @default.
• W163567197 hasConcept C86803240 @default.
• W163567197 hasConceptScore W163567197C104317684 @default.
• W163567197 hasConceptScore W163567197C142724271 @default.
• W163567197 hasConceptScore W163567197C185592680 @default.
• W163567197 hasConceptScore W163567197C190283241 @default.
• W163567197 hasConceptScore W163567197C203522944 @default.
• W163567197 hasConceptScore W163567197C2776262904 @default.
• W163567197 hasConceptScore W163567197C2776302905 @default.
• W163567197 hasConceptScore W163567197C2776694085 @default.
• W163567197 hasConceptScore W163567197C2778305200 @default.
• W163567197 hasConceptScore W163567197C31573885 @default.
• W163567197 hasConceptScore W163567197C502942594 @default.
• W163567197 hasConceptScore W163567197C54355233 @default.
• W163567197 hasConceptScore W163567197C55493867 @default.
• W163567197 hasConceptScore W163567197C62112901 @default.
• W163567197 hasConceptScore W163567197C64927066 @default.
• W163567197 hasConceptScore W163567197C71924100 @default.

• next