FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1636192709> ?p ?o ?g. }

• W1636192709 endingPage "1489" @default.
• W1636192709 startingPage "1483" @default.
• W1636192709 abstract "Minimal hepatic encephalopathy (MHE) is associated with falls, traffic accidents, and overt HE. However, the association with survival is controversial. We assessed the effects of MHE on the long-term survival of patients with cirrhosis.We performed a prospective study of 117 consecutive patients with cirrhosis seen at a tertiary hospital in Seville, Spain (estimation cohort), followed by a validation study of 114 consecutive patients with cirrhosis seen at 4 hospitals in Spain from January 2004 through December 2007. Patients were examined every 6 months at outpatient clinics through December 2013 (follow-up periods of 5 ± 2.8 y and 4.4 ± 3.9 y for each group, respectively). Cirrhosis was identified by liver biopsy, ultrasound, endoscopic analysis, and biochemical parameters. Liver dysfunction was determined based on model for end-stage liver disease (MELD) and Child-Pugh scores. All patients were administered the critical flicker frequency (CFF) test and psychometric hepatic encephalopathy scores were used to detect MHE. Survival curves were compared using the log-rank test and multivariable analysis was performed using Cox proportional hazards models.The distributions of Child-Pugh scores were as follows: 66% class A, 31% class B, and 3% class C in the estimation cohort, and 50% class A, 32% class B, and 18% class C in the validation cohort. In the estimation cohort, 24 of 35 patients (68.6%) with a CFF score less than 39 Hz survived for 5 years, whereas 50 of 61 patients (82%) with a CFF score of 39 Hz or higher survived during the follow-up period (log-rank score, 5.07; P = .024). Psychometric hepatic encephalopathy scores did not correlate with survival. In multivariable analysis, older age (hazard ratio [HR], 1.07; 95% confidence interval [CI], 1.02-1.12; P = .009), CFF score less than 39 Hz (HR, 4.36; 95% CI, 1.67-11.37; P = .003), and MELD score (HR, 1.40; 95% CI, 1.21-1.63; P = .0001) were associated independently with survival during the follow-up period. In the validation cohort, CFF score less than 39 Hz and MELD score also were associated with patient survival during the follow-up period. MHE had no effect on the survival of patients with MELD scores less than 10 (among patients with CFF scores ≥39 Hz, 94.5% survived for 5 years vs 91.9% of patients with CFF scores <39 Hz; log-rank score, 0.64; P = .423). Fewer patients with MELD scores of 10-15 and MHE survived for 5 years (44.4%; 12 of 27) than those with MELD scores greater than 15 without MHE (61.5%; 8 of 13) (P < .05). Only 2 of 12 patients (16.7%) with MELD scores of 15 or higher and MHE survived for 5 years (log-rank score, 90.56; P = .0001).MHE is associated with a reduced 5-year survival rate of patients with cirrhosis. Evaluation of MHE could help predict survival times and outcomes of patients with specific MELD scores. The CFF could help physicians determine prognoses of patients with cirrhosis." @default.
• W1636192709 created "2016-06-24" @default.
• W1636192709 creator A5027940000 @default.
• W1636192709 creator A5037480677 @default.
• W1636192709 creator A5046081761 @default.
• W1636192709 creator A5052253956 @default.
• W1636192709 creator A5075040560 @default.
• W1636192709 creator A5080031484 @default.
• W1636192709 creator A5083797541 @default.
• W1636192709 date "2015-11-01" @default.
• W1636192709 modified "2023-10-01" @default.
• W1636192709 title "Minimal Hepatic Encephalopathy and Critical Flicker Frequency Are Associated With Survival of Patients With Cirrhosis" @default.
• W1636192709 cites W1965008709 @default.
• W1636192709 cites W1971689007 @default.
• W1636192709 cites W1973051170 @default.
• W1636192709 cites W1973661816 @default.
• W1636192709 cites W1988280368 @default.
• W1636192709 cites W1993226016 @default.
• W1636192709 cites W1997418839 @default.
• W1636192709 cites W2012304194 @default.
• W1636192709 cites W2012523936 @default.
• W1636192709 cites W2015243077 @default.
• W1636192709 cites W2016627047 @default.
• W1636192709 cites W2025601697 @default.
• W1636192709 cites W2025789176 @default.
• W1636192709 cites W2026352845 @default.
• W1636192709 cites W2031254637 @default.
• W1636192709 cites W2035189051 @default.
• W1636192709 cites W2038045630 @default.
• W1636192709 cites W2039560063 @default.
• W1636192709 cites W2043894481 @default.
• W1636192709 cites W2054911815 @default.
• W1636192709 cites W2069627319 @default.
• W1636192709 cites W2072139861 @default.
• W1636192709 cites W2075307181 @default.
• W1636192709 cites W2078166385 @default.
• W1636192709 cites W2079385693 @default.
• W1636192709 cites W2083754290 @default.
• W1636192709 cites W2092488871 @default.
• W1636192709 cites W2093694511 @default.
• W1636192709 cites W2105932465 @default.
• W1636192709 cites W2140396673 @default.
• W1636192709 cites W2143262486 @default.
• W1636192709 cites W2148609006 @default.
• W1636192709 cites W2166834388 @default.
• W1636192709 cites W2167639183 @default.
• W1636192709 cites W2576135049 @default.
• W1636192709 doi "https://doi.org/10.1053/j.gastro.2015.07.067" @default.
• W1636192709 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26299413" @default.
• W1636192709 hasPublicationYear "2015" @default.
• W1636192709 type Work @default.
• W1636192709 sameAs 1636192709 @default.
• W1636192709 citedByCount "100" @default.
• W1636192709 countsByYear W16361927092015 @default.
• W1636192709 countsByYear W16361927092016 @default.
• W1636192709 countsByYear W16361927092017 @default.
• W1636192709 countsByYear W16361927092018 @default.
• W1636192709 countsByYear W16361927092019 @default.
• W1636192709 countsByYear W16361927092020 @default.
• W1636192709 countsByYear W16361927092021 @default.
• W1636192709 countsByYear W16361927092022 @default.
• W1636192709 countsByYear W16361927092023 @default.
• W1636192709 crossrefType "journal-article" @default.
• W1636192709 hasAuthorship W1636192709A5027940000 @default.
• W1636192709 hasAuthorship W1636192709A5037480677 @default.
• W1636192709 hasAuthorship W1636192709A5046081761 @default.
• W1636192709 hasAuthorship W1636192709A5052253956 @default.
• W1636192709 hasAuthorship W1636192709A5075040560 @default.
• W1636192709 hasAuthorship W1636192709A5080031484 @default.
• W1636192709 hasAuthorship W1636192709A5083797541 @default.
• W1636192709 hasConcept C126322002 @default.
• W1636192709 hasConcept C141071460 @default.
• W1636192709 hasConcept C188816634 @default.
• W1636192709 hasConcept C2777075537 @default.
• W1636192709 hasConcept C2777214474 @default.
• W1636192709 hasConcept C2778621155 @default.
• W1636192709 hasConcept C2780325230 @default.
• W1636192709 hasConcept C50382708 @default.
• W1636192709 hasConcept C71924100 @default.
• W1636192709 hasConcept C72563966 @default.
• W1636192709 hasConcept C90924648 @default.
• W1636192709 hasConceptScore W1636192709C126322002 @default.
• W1636192709 hasConceptScore W1636192709C141071460 @default.
• W1636192709 hasConceptScore W1636192709C188816634 @default.
• W1636192709 hasConceptScore W1636192709C2777075537 @default.
• W1636192709 hasConceptScore W1636192709C2777214474 @default.
• W1636192709 hasConceptScore W1636192709C2778621155 @default.
• W1636192709 hasConceptScore W1636192709C2780325230 @default.
• W1636192709 hasConceptScore W1636192709C50382708 @default.
• W1636192709 hasConceptScore W1636192709C71924100 @default.
• W1636192709 hasConceptScore W1636192709C72563966 @default.
• W1636192709 hasConceptScore W1636192709C90924648 @default.
• W1636192709 hasIssue "6" @default.
• W1636192709 hasLocation W16361927091 @default.
• W1636192709 hasLocation W16361927092 @default.
• W1636192709 hasOpenAccess W1636192709 @default.
• W1636192709 hasPrimaryLocation W16361927091 @default.
• W1636192709 hasRelatedWork W2006729455 @default.

• next