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- W1637993497 abstract "The 3 D structure of Cas9 bound with sgRNA was solved by X-ray crystal-structure analysis. The conformation change in SpyCas9 upon binding to sgRNA changes Cas9 to target-DNA-recognition mode in which seed segments in sgRNA are pre-ordered in an A-type conformation." @default.
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- W1637993497 date "2015-09-09" @default.
- W1637993497 modified "2023-09-23" @default.
- W1637993497 title "Pre-organized Guide RNA in the Cas9 Complex Is Ready for the Selection of Target Double-Stranded DNA" @default.
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- W1637993497 doi "https://doi.org/10.1002/cbic.201500424" @default.
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