Matches in SemOpenAlex for { <https://semopenalex.org/work/W1639518309> ?p ?o ?g. }
- W1639518309 abstract "Systemic lupus erythematosus (SLE) is characterised by increased venous and arterial thrombotic risk. Although antiphospholipid antibodies (APAs) have been shown to be related with thrombotic tendency in these patients, in more than 40% of them, thrombosis occurs without the presence of such antibodies. We analysed the association of venous and arterial thrombotic events with acquired (anticardiolipin antibodies (ACAs) and lupus anticoagulant (LA)) and inherited (antithrombin (AT), protein C (PC), protein S (PS) deficiencies, factor V Leiden and the prothrombin G20210A mutation), thrombophilic risk factors in 86 SLE patients and 89 healthy controls. Patients showed a higher significant percentage of ACAs titres IgG>41 GPL u/ml and LA than controls (P=0.009; P<0.001, respectively), although no differences in AT, PC, PS deficiencies, factor V Leiden and prothrombin G20210A mutation was observed (P>0.05). When patients with and without thrombosis were compared, those with thrombosis showed a statistically higher percentage of ACAs IgG>41 GPL u/ml and LA (P=0.048; P=0.001, respectively), OR 4.33; 95% CI 1.01-18.50 and OR 11.57; 95% CI 3.28-40.75, respectively. When venous and arterial thrombotic events were considered separately, the presence of LA constituted a risk factor for arterial thrombosis (P=0.010), OR 11.33; 95% CI 1.86-68.89, as well as for venous thrombosis (P=0.005), OR 10.15; 95% CI 2.12-48.64, while ACAs IgG>41 GPL u/ml on their own, were not associated with arterial or venous thrombosis (P=0.142, P=0.233, respectively). In addition inherited thrombophilic risk factors AT, PC, PS deficiencies, factor V Leiden and PT G20210A mutation do not seem to increase thrombotic risk in SLE patients." @default.
- W1639518309 created "2016-06-24" @default.
- W1639518309 creator A5010184382 @default.
- W1639518309 creator A5021978850 @default.
- W1639518309 creator A5026232495 @default.
- W1639518309 creator A5053484499 @default.
- W1639518309 creator A5057986151 @default.
- W1639518309 creator A5058115278 @default.
- W1639518309 creator A5071063033 @default.
- W1639518309 creator A5078405232 @default.
- W1639518309 creator A5078413600 @default.
- W1639518309 creator A5091085793 @default.
- W1639518309 date "2008-01-01" @default.
- W1639518309 modified "2023-10-16" @default.
- W1639518309 title "Thrombotic events in systemic lupus erythematosus. Its association with acquired and inherited thrombophilic defects" @default.
- W1639518309 cites W133091976 @default.
- W1639518309 cites W1531281563 @default.
- W1639518309 cites W1596313173 @default.
- W1639518309 cites W1779080612 @default.
- W1639518309 cites W191524293 @default.
- W1639518309 cites W1972058538 @default.
- W1639518309 cites W1984327861 @default.
- W1639518309 cites W2015087086 @default.
- W1639518309 cites W2030638382 @default.
- W1639518309 cites W2046211002 @default.
- W1639518309 cites W2052530127 @default.
- W1639518309 cites W2057110535 @default.
- W1639518309 cites W2059943793 @default.
- W1639518309 cites W2060905334 @default.
- W1639518309 cites W2069794594 @default.
- W1639518309 cites W2115496024 @default.
- W1639518309 cites W2133869208 @default.
- W1639518309 cites W2143193067 @default.
- W1639518309 cites W2157876594 @default.
- W1639518309 cites W2409904527 @default.
- W1639518309 cites W2462261788 @default.
- W1639518309 cites W2462341569 @default.
- W1639518309 cites W1918617447 @default.
- W1639518309 doi "https://doi.org/10.3233/ch-2008-1117" @default.
- W1639518309 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19029633" @default.
- W1639518309 hasPublicationYear "2008" @default.
- W1639518309 type Work @default.
- W1639518309 sameAs 1639518309 @default.
- W1639518309 citedByCount "10" @default.
- W1639518309 countsByYear W16395183092012 @default.
- W1639518309 countsByYear W16395183092017 @default.
- W1639518309 countsByYear W16395183092020 @default.
- W1639518309 crossrefType "journal-article" @default.
- W1639518309 hasAuthorship W1639518309A5010184382 @default.
- W1639518309 hasAuthorship W1639518309A5021978850 @default.
- W1639518309 hasAuthorship W1639518309A5026232495 @default.
- W1639518309 hasAuthorship W1639518309A5053484499 @default.
- W1639518309 hasAuthorship W1639518309A5057986151 @default.
- W1639518309 hasAuthorship W1639518309A5058115278 @default.
- W1639518309 hasAuthorship W1639518309A5071063033 @default.
- W1639518309 hasAuthorship W1639518309A5078405232 @default.
- W1639518309 hasAuthorship W1639518309A5078413600 @default.
- W1639518309 hasAuthorship W1639518309A5091085793 @default.
- W1639518309 hasConcept C126322002 @default.
- W1639518309 hasConcept C159654299 @default.
- W1639518309 hasConcept C203014093 @default.
- W1639518309 hasConcept C2776874634 @default.
- W1639518309 hasConcept C2777175894 @default.
- W1639518309 hasConcept C2777557582 @default.
- W1639518309 hasConcept C2779026020 @default.
- W1639518309 hasConcept C2780011451 @default.
- W1639518309 hasConcept C2780022809 @default.
- W1639518309 hasConcept C2780868729 @default.
- W1639518309 hasConcept C50440223 @default.
- W1639518309 hasConcept C71924100 @default.
- W1639518309 hasConcept C90924648 @default.
- W1639518309 hasConceptScore W1639518309C126322002 @default.
- W1639518309 hasConceptScore W1639518309C159654299 @default.
- W1639518309 hasConceptScore W1639518309C203014093 @default.
- W1639518309 hasConceptScore W1639518309C2776874634 @default.
- W1639518309 hasConceptScore W1639518309C2777175894 @default.
- W1639518309 hasConceptScore W1639518309C2777557582 @default.
- W1639518309 hasConceptScore W1639518309C2779026020 @default.
- W1639518309 hasConceptScore W1639518309C2780011451 @default.
- W1639518309 hasConceptScore W1639518309C2780022809 @default.
- W1639518309 hasConceptScore W1639518309C2780868729 @default.
- W1639518309 hasConceptScore W1639518309C50440223 @default.
- W1639518309 hasConceptScore W1639518309C71924100 @default.
- W1639518309 hasConceptScore W1639518309C90924648 @default.
- W1639518309 hasLocation W16395183091 @default.
- W1639518309 hasLocation W16395183092 @default.
- W1639518309 hasOpenAccess W1639518309 @default.
- W1639518309 hasPrimaryLocation W16395183091 @default.
- W1639518309 hasRelatedWork W1639518309 @default.
- W1639518309 hasRelatedWork W191524293 @default.
- W1639518309 hasRelatedWork W2038335180 @default.
- W1639518309 hasRelatedWork W2060366265 @default.
- W1639518309 hasRelatedWork W2066542021 @default.
- W1639518309 hasRelatedWork W20724425 @default.
- W1639518309 hasRelatedWork W2106011474 @default.
- W1639518309 hasRelatedWork W2315578003 @default.
- W1639518309 hasRelatedWork W2329867113 @default.
- W1639518309 hasRelatedWork W2398887896 @default.
- W1639518309 isParatext "false" @default.
- W1639518309 isRetracted "false" @default.