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- W1640306093 abstract "Background: Continuous invasive arterial blood pressure (IBP) monitoring remains the accepted gold standard for blood pressure monitoring because of its high accuracy. Several disadvantages of this method motivate the use of noninvasive intermittent blood pressure (NIBP) in most anesthesia cases despite its lower accuracy and intermittent nature. A recently introduced alternative (Nexfin®, BMEye, Amsterdam) is based on a cuff-manometer and light-absorption sensor in a finger cuff and allows for noninvasive continuous blood pressure monitoring. The aim of this study is to evaluate the accuracy of the MAP assessed by the Nexfin® monitor and NiBP in comparison with the IBP (gold standard). Methods: After local IRB approval and written Informed Consent, 110 patients under general anesthesia necessitating IBP were included. For a period of 30 minutes during the operation, the mean arterial pressure (MAP) determined by IBP, NIBP and NIBPnexfin was continuously recorded. NIBP measurement frequency was set at 5 minutes. The finger cuff of the Nexfin device was always applied at the intermediate phalanx. Analysis of 30-second median pressure values was performed at 5-minute intervals. Absolute bias as a measure of accuracy was calculated as: MAPNexfin-MAPIBP or as MAPNIBP-MAPIBP. Precision, as a measure of repeatability, was represented by calculation of the standard deviation of the absolute bias. The limits of agreement (1.96xSD of the bias) were also calculated. Results: Nexfin was on the ipsilateral/contralateral hand of the IBP in 70/40 patients undergoing elective surgery. Mean(SD) age was 63(13) years in 68/42 male/female patients. The evolution of the mean and individual values of the bias of the MAPNexfin and MAPNIBP and respective 10th and 90th percentile are shown in figure 1. Figure 2 shows the mean bias, precision and limits of agreement of MAPNexfin at 30 minutes. Figure 2 and Table 1 show the Bland-Altman analysis of MAPNexfin and MAPNIBP at different time points during the assessment. Conclusion: The numerical value of MAPNexfin has superior accuracy than MAPNIBP, in addition to the obvious advantage of continuous measurement. The accuracy of the MAPNexfin is stable over the course of the measurement without requiring a long equilibration time, and with satisfactory accuracy for most procedures." @default.
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- W1640306093 date "2013-03-07" @default.
- W1640306093 modified "2023-09-24" @default.
- W1640306093 title "Validation of continuous noninvasive arterial blood pressure measurements during general anesthesia" @default.
- W1640306093 doi "https://doi.org/10.7490/f1000research.1092944.1" @default.
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