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- W164039264 abstract "Cardiovascular disease is the number one cause of mortality in the Western world, with heart failure representing one of the fastest growing subgroups over the past decade. Heart failure, the progressive loss of cardiac contractile performance resulting in an inability to pump an adequate supply of systemic blood, affects an estimated 5 million Americans with estimated medical costs of $21–$50 billion per year1. A number of common disease disease stimuli can induce heart failure, including hypertension, myocardial infarction, ischemia associated with coronary artery disease, congenital malformation, familial hypertrophic and dilated cardiomyopathies and diabetic cardiomyopathy. Systolic and diastolic dysfunction is common in patients suffering from coronary artery disease and hypertension and is a main cause of heart failure. Hypertrophic growth of cardiomyocytes also occurs in many forms of heart failure and may contribute to the pathogenesis of the failure state2." @default.
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- W164039264 date "2008-01-01" @default.
- W164039264 modified "2023-09-25" @default.
- W164039264 title "The Role of Tropomyosin in Heart Disease" @default.
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- W164039264 doi "https://doi.org/10.1007/978-0-387-85766-4_11" @default.
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