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- W164046712 abstract "No AccessJournal of Urology1 Apr 1987Testicular Cancer: Prognostic Implications of Vascular Invasion W. Hoeltl, D. Kosak, J. Pont, R. Hawel, E. Machacek, M. Schemper, N. Honetz, and M. Marberger W. HoeltlW. Hoeltl More articles by this author , D. KosakD. Kosak More articles by this author , J. PontJ. Pont More articles by this author , R. HawelR. Hawel More articles by this author , E. MachacekE. Machacek More articles by this author , M. SchemperM. Schemper More articles by this author , N. HonetzN. Honetz More articles by this author , and M. MarbergerM. Marberger More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)44174-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail In a retrospective study the primary tumors of 33 patients with seminomas and 53 with nonseminomatous germ cell tumors were re-evaluated for vascular invasion. The significance of vascular invasion was analyzed in respect to the appearance of visceral metastases and the effect of adjuvant chemotherapy. Vascular invasion was demonstrated in 27 per cent of the patients with seminomas and 53 per cent with nonseminomatous germ cell testis tumors, while visceral metastases appeared in 9 and 32 per cent, respectively. Without adjuvant chemotherapy all 13 patients with nonseminomatous germ cell testis tumors and vascular invasion had metastases, compared to only 3 of 13 without vascular invasion (p less than 0.0005). Of 9 patients with seminoma and vascular invasion 3 had tumor progression, compared to 1 of 24 without vascular invasion (p greater than 0.05). With adjuvant chemotherapy only 1 of 15 patients (7 per cent) with nonseminomatous germ cell testis tumors and vascular invasion had metastases, compared to 100 per cent of 13 without this treatment. No significant correlation was noted between pT stage versus vascular invasion and pT stage versus tumor progression. The results demonstrate the importance of vascular invasion in the staging of and choice of treatment for early nonseminomatous germ cell testis tumors. © 1987 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byHoeltl W (2018) Re: Prognostic Assessment in Nonseminomatous Testicular Cancer: Implications for Therapy, by P. J. Hesketh and R. J. Krane, J. Urol., 144: 1–9, 1990Journal of Urology, VOL. 146, NO. 6, (1619-1620), Online publication date: 1-Dec-1991.Marks L, Rutgers J, Shipley W, Walker T, Stracher M, Waltman A and Geller S (2018) Testicular Seminoma: Clinical and Pathological Features that May Predict Para-Aortic Lymph Node MetastasesJournal of Urology, VOL. 143, NO. 3, (524-527), Online publication date: 1-Mar-1990. Volume 137Issue 4April 1987Page: 683-685 Advertisement Copyright & Permissions© 1987 by The American Urological Association Education and Research, Inc.MetricsAuthor Information W. Hoeltl More articles by this author D. Kosak More articles by this author J. Pont More articles by this author R. Hawel More articles by this author E. Machacek More articles by this author M. Schemper More articles by this author N. Honetz More articles by this author M. Marberger More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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- W164046712 title "Testicular Cancer: Prognostic Implications of Vascular Invasion" @default.
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