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- W1640875843 abstract "The peripheral nervous system (PNS) of the Drosophila embryo is especially suited for investigating the specification of neuronal identity: the PNS consists of a relatively simple but diverse set of individually identified sensory neurons; mutants, including embryonic lethals, can be readily generated and analyzed; and axon growth can potentially be followed from the earliest stages. We have developed a staining method to reveal the central projections of the full set of sensory neurons in the preterminal abdominal segments of the embryo. The sensory neurons exhibit modality-specific axonal projections in the CNS. The axons of external sense (es) organ neurons, primarily tactile in function, are restricted to a particular region within each neuromere and exhibit a somatotopic mapping within the CNS. The axons of stretch-receptive chordotonal (ch) organs project into a discrete longitudinal fascicle. Sensory neurons with multiple-branched dendrites (md neurons) project into a separate fascicle. A small number of md neurons have distinctive dorsal-projecting axonal processes in the CNS. A classification of sensory neurons based on their axon morphology correlates closely with the identity of the proneural gene responsible for their generation, suggesting that proneural genes play a central role in determining neuronal identity in the PNS of the embryo." @default.
- W1640875843 created "2016-06-24" @default.
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- W1640875843 date "1995-03-01" @default.
- W1640875843 modified "2023-09-26" @default.
- W1640875843 title "Central projections of sensory neurons in the Drosophila embryo correlate with sensory modality, soma position, and proneural gene function" @default.
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- W1640875843 doi "https://doi.org/10.1523/jneurosci.15-03-01755.1995" @default.
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