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• W1641088894 abstract "This chapter discusses the role of hypothalamic noradrenergic neurons in food intake regulation. To investigate the differential involvement of adrenergic neurons in different parts of the hypothalamus the chapter mentions experiments in which catecholaminergic systems in different loci is selectively destroyed by means of 6-hydroxydopamine (6-OHDA). A specific technique used in investigating hypothalamic neural systems is the technique of injecting small amounts of chemicals that are known to affect in a specific way a particular type of neuron, directly into the hypothalamus and then observe their effects in anaesthetized and unrestrained subjects. A chronic cannula is implanted in the brain that allows for repeated drug injections into a specific site when the animal has recovered from the operation. The hypothesis of an inhibitory action of the 8-receptors rests upon the concept of the LH as a “feeding” center, a concept that has originated mainly because lesions in the lateral hypothalamus caused aphagia and adipsia, and because electrical stimulation of the LH caused stimulus bound eating." @default.
• W1641088894 created "2016-06-24" @default.
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• W1641088894 date "1974-01-01" @default.
• W1641088894 modified "2023-09-27" @default.
• W1641088894 title "The Role of Hypothalamic Noradrenergic Neurons in Food Intake Regulation" @default.
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• W1641088894 doi "https://doi.org/10.1016/s0079-6123(08)61920-2" @default.
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