FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1644256013> ?p ?o ?g. }

• W1644256013 endingPage "140" @default.
• W1644256013 startingPage "135" @default.
• W1644256013 abstract "Abstract Background: Cardiovascular disease has long been associated with poor neurocognitive outcome, with multiple pathophysiological mechanisms that are linked to cognitive impairment in older adults. Although less frequently examined, insulin dysregulation is known to affect vascular function and the associated brain dysfunction in cardiovascular disease. Accordingly, genetic factors tied to insulin regulation may make certain people with cardiovascular disease more susceptible to cognitive dysfunction. Specifically, the calmodulin‐binding transcription activator 1 ( CAMTA1 ) genotype, which has been examined as a risk factor for Type 2 diabetes and has been linked to reduced episodic memory performance in healthy young adults, is a potential candidate gene. Methods: Blood samples were obtained from 113 older adults with cardiovascular disease who also underwent neuropsychological testing. Carriers of either one or two copies of the T allele of CAMTA1 were categorized into one group ( n = 63), whereas non‐carriers were categorized into a second group ( n = 50). Results: Analyses showed that carriers of the T allele performed more poorly on tests of attention, executive function, and psychomotor speed, but not on tests of memory. Carriers of the T allele also performed more poorly on a measure of global cognitive function. Conclusions: Results indicate that CAMTA1 genotype is associated with cognitive function in older adults with cardiovascular disease, because carriers of the T allele performed more poorly on tests of attention, executive function, and psychomotor speed. Contrary to expectations, there were no differences in memory performance among carriers and non‐carriers of the T allele. Given these mixed findings, further studies are necessary to elucidate the association between CAMTA1 and cognition, particularly gene expression and neuroimaging studies." @default.
• W1644256013 created "2016-06-24" @default.
• W1644256013 creator A5013689337 @default.
• W1644256013 creator A5021789074 @default.
• W1644256013 creator A5034369765 @default.
• W1644256013 creator A5035290107 @default.
• W1644256013 creator A5045468158 @default.
• W1644256013 creator A5048589387 @default.
• W1644256013 creator A5050132130 @default.
• W1644256013 creator A5072862594 @default.
• W1644256013 creator A5076777565 @default.
• W1644256013 date "2011-06-15" @default.
• W1644256013 modified "2023-10-16" @default.
• W1644256013 title "CAMTA1 T polymorphism is associated with neuropsychological test performance in older adults with cardiovascular disease" @default.
• W1644256013 cites W1847168837 @default.
• W1644256013 cites W1963629293 @default.
• W1644256013 cites W1971745836 @default.
• W1644256013 cites W2000555003 @default.
• W1644256013 cites W2009586628 @default.
• W1644256013 cites W2023280641 @default.
• W1644256013 cites W2024139795 @default.
• W1644256013 cites W2025143098 @default.
• W1644256013 cites W2050970964 @default.
• W1644256013 cites W2055524400 @default.
• W1644256013 cites W2071692287 @default.
• W1644256013 cites W2072746534 @default.
• W1644256013 cites W2088617938 @default.
• W1644256013 cites W2090553836 @default.
• W1644256013 cites W2092879681 @default.
• W1644256013 cites W2099544649 @default.
• W1644256013 cites W2122281432 @default.
• W1644256013 cites W2135464821 @default.
• W1644256013 cites W2141505663 @default.
• W1644256013 cites W2142602024 @default.
• W1644256013 cites W2147483910 @default.
• W1644256013 cites W2149369886 @default.
• W1644256013 cites W2150277101 @default.
• W1644256013 cites W2157813392 @default.
• W1644256013 cites W2768019923 @default.
• W1644256013 doi "https://doi.org/10.1111/j.1479-8301.2011.00357.x" @default.
• W1644256013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21951953" @default.
• W1644256013 hasPublicationYear "2011" @default.
• W1644256013 type Work @default.
• W1644256013 sameAs 1644256013 @default.
• W1644256013 citedByCount "13" @default.
• W1644256013 countsByYear W16442560132012 @default.
• W1644256013 countsByYear W16442560132014 @default.
• W1644256013 countsByYear W16442560132015 @default.
• W1644256013 countsByYear W16442560132016 @default.
• W1644256013 countsByYear W16442560132017 @default.
• W1644256013 countsByYear W16442560132020 @default.
• W1644256013 countsByYear W16442560132022 @default.
• W1644256013 countsByYear W16442560132023 @default.
• W1644256013 crossrefType "journal-article" @default.
• W1644256013 hasAuthorship W1644256013A5013689337 @default.
• W1644256013 hasAuthorship W1644256013A5021789074 @default.
• W1644256013 hasAuthorship W1644256013A5034369765 @default.
• W1644256013 hasAuthorship W1644256013A5035290107 @default.
• W1644256013 hasAuthorship W1644256013A5045468158 @default.
• W1644256013 hasAuthorship W1644256013A5048589387 @default.
• W1644256013 hasAuthorship W1644256013A5050132130 @default.
• W1644256013 hasAuthorship W1644256013A5072862594 @default.
• W1644256013 hasAuthorship W1644256013A5076777565 @default.
• W1644256013 hasBestOaLocation W16442560131 @default.
• W1644256013 hasConcept C104317684 @default.
• W1644256013 hasConcept C118552586 @default.
• W1644256013 hasConcept C126322002 @default.
• W1644256013 hasConcept C135763542 @default.
• W1644256013 hasConcept C14216870 @default.
• W1644256013 hasConcept C15744967 @default.
• W1644256013 hasConcept C164953862 @default.
• W1644256013 hasConcept C169900460 @default.
• W1644256013 hasConcept C172467417 @default.
• W1644256013 hasConcept C180754005 @default.
• W1644256013 hasConcept C2779134260 @default.
• W1644256013 hasConcept C2779483572 @default.
• W1644256013 hasConcept C54355233 @default.
• W1644256013 hasConcept C71924100 @default.
• W1644256013 hasConcept C86803240 @default.
• W1644256013 hasConceptScore W1644256013C104317684 @default.
• W1644256013 hasConceptScore W1644256013C118552586 @default.
• W1644256013 hasConceptScore W1644256013C126322002 @default.
• W1644256013 hasConceptScore W1644256013C135763542 @default.
• W1644256013 hasConceptScore W1644256013C14216870 @default.
• W1644256013 hasConceptScore W1644256013C15744967 @default.
• W1644256013 hasConceptScore W1644256013C164953862 @default.
• W1644256013 hasConceptScore W1644256013C169900460 @default.
• W1644256013 hasConceptScore W1644256013C172467417 @default.
• W1644256013 hasConceptScore W1644256013C180754005 @default.
• W1644256013 hasConceptScore W1644256013C2779134260 @default.
• W1644256013 hasConceptScore W1644256013C2779483572 @default.
• W1644256013 hasConceptScore W1644256013C54355233 @default.
• W1644256013 hasConceptScore W1644256013C71924100 @default.
• W1644256013 hasConceptScore W1644256013C86803240 @default.
• W1644256013 hasIssue "3" @default.
• W1644256013 hasLocation W16442560131 @default.
• W1644256013 hasLocation W16442560132 @default.
• W1644256013 hasOpenAccess W1644256013 @default.

• next