FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1645376918> ?p ?o ?g. }

• W1645376918 abstract "Motivation: ``Molecular signatures'' or ``gene-expression signatures'' are used to predict patients' characteristics using data from coexpressed genes. Signatures can enhance understanding about biological mechanisms and have diagnostic use. However, available methods to search for signatures fail to address key requirements of signatures, especially the discovery of sets of tightly coexpressed genes. Results: After suggesting an operational definition of signature, we develop a method that fulfills these requirements, returning sets of tightly coexpressed genes with good predictive performance. This method can also identify when the data are inconsistent with the hypothesis of a few, stable, easily interpretable sets of coexpressed genes. Identification of molecular signatures in some widely used data sets is questionable under this simple model, which emphasizes the needed for further work on the operationalization of the biological model and the assessment of the stability of putative signatures. Availability: The code (R with C++) is available from this http URL under the GNU GPL." @default.
• W1645376918 created "2016-06-24" @default.
• W1645376918 creator A5061700518 @default.
• W1645376918 creator A5083551215 @default.
• W1645376918 date "2004-01-30" @default.
• W1645376918 modified "2023-09-27" @default.
• W1645376918 title "Molecular Signatures from Gene Expression Data" @default.
• W1645376918 cites W1480376833 @default.
• W1645376918 cites W1490229695 @default.
• W1645376918 cites W1529972356 @default.
• W1645376918 cites W1608932033 @default.
• W1645376918 cites W1792175597 @default.
• W1645376918 cites W1922999930 @default.
• W1645376918 cites W1966701961 @default.
• W1645376918 cites W1976927254 @default.
• W1645376918 cites W1978483425 @default.
• W1645376918 cites W1985038830 @default.
• W1645376918 cites W1989076816 @default.
• W1645376918 cites W1989539998 @default.
• W1645376918 cites W1995023148 @default.
• W1645376918 cites W1995945562 @default.
• W1645376918 cites W1998558965 @default.
• W1645376918 cites W2002666062 @default.
• W1645376918 cites W2004308954 @default.
• W1645376918 cites W2005363197 @default.
• W1645376918 cites W2008233728 @default.
• W1645376918 cites W2009435671 @default.
• W1645376918 cites W2022441134 @default.
• W1645376918 cites W2023416945 @default.
• W1645376918 cites W2024765216 @default.
• W1645376918 cites W2039634280 @default.
• W1645376918 cites W2043235003 @default.
• W1645376918 cites W2059313996 @default.
• W1645376918 cites W2064208261 @default.
• W1645376918 cites W2079775628 @default.
• W1645376918 cites W2084341220 @default.
• W1645376918 cites W2087998083 @default.
• W1645376918 cites W2088851040 @default.
• W1645376918 cites W2092868756 @default.
• W1645376918 cites W2096763239 @default.
• W1645376918 cites W2096863518 @default.
• W1645376918 cites W2097879961 @default.
• W1645376918 cites W2098770874 @default.
• W1645376918 cites W2104969279 @default.
• W1645376918 cites W2106273198 @default.
• W1645376918 cites W2107956883 @default.
• W1645376918 cites W2108043112 @default.
• W1645376918 cites W2108728387 @default.
• W1645376918 cites W2109363337 @default.
• W1645376918 cites W2115709314 @default.
• W1645376918 cites W2116449426 @default.
• W1645376918 cites W2117812871 @default.
• W1645376918 cites W2124201592 @default.
• W1645376918 cites W2128985829 @default.
• W1645376918 cites W2129476886 @default.
• W1645376918 cites W2137476312 @default.
• W1645376918 cites W2138550913 @default.
• W1645376918 cites W2139212933 @default.
• W1645376918 cites W2139501760 @default.
• W1645376918 cites W2139954541 @default.
• W1645376918 cites W2141025089 @default.
• W1645376918 cites W2141823231 @default.
• W1645376918 cites W2147246240 @default.
• W1645376918 cites W2152393933 @default.
• W1645376918 cites W2153635508 @default.
• W1645376918 cites W2155236584 @default.
• W1645376918 cites W2157531738 @default.
• W1645376918 cites W2157875785 @default.
• W1645376918 cites W2160450758 @default.
• W1645376918 cites W2161349318 @default.
• W1645376918 cites W2166902257 @default.
• W1645376918 cites W2168561598 @default.
• W1645376918 cites W2174658582 @default.
• W1645376918 cites W2317938141 @default.
• W1645376918 cites W2414133885 @default.
• W1645376918 cites W3099514962 @default.
• W1645376918 cites W1593486402 @default.
• W1645376918 hasPublicationYear "2004" @default.
• W1645376918 type Work @default.
• W1645376918 sameAs 1645376918 @default.
• W1645376918 citedByCount "0" @default.
• W1645376918 crossrefType "posted-content" @default.
• W1645376918 hasAuthorship W1645376918A5061700518 @default.
• W1645376918 hasAuthorship W1645376918A5083551215 @default.
• W1645376918 hasConcept C104317684 @default.
• W1645376918 hasConcept C111472728 @default.
• W1645376918 hasConcept C116834253 @default.
• W1645376918 hasConcept C124101348 @default.
• W1645376918 hasConcept C138885662 @default.
• W1645376918 hasConcept C2524010 @default.
• W1645376918 hasConcept C2779696439 @default.
• W1645376918 hasConcept C33923547 @default.
• W1645376918 hasConcept C41008148 @default.
• W1645376918 hasConcept C54355233 @default.
• W1645376918 hasConcept C59822182 @default.
• W1645376918 hasConcept C60644358 @default.
• W1645376918 hasConcept C70721500 @default.
• W1645376918 hasConcept C86803240 @default.
• W1645376918 hasConcept C9354725 @default.
• W1645376918 hasConceptScore W1645376918C104317684 @default.

• next