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- W164582092 abstract "This chapter describes the surgery in nonseminomatous germ cell tumors of the testis. Primary retroperitoneal lymph-node dissection (RPLND) in low-stage disease provides pathological staging and has a curative potentiality. Postoperative morbidity is considered to be low, with the exception of ejaculatory failure. In a study described in the chapter, it was investigated whether clinico-pathological ringings registered at the time of orchiectomy were predictive for retroperitoneal metastases at surgical staging and for subsequent relapses in 279 consecutive patients with clinical stage I nonseminomatous germ cell tumors (NSGCT) of the testis. By multivariate logistic regression analysis, vascular invasion, and normal preorchiectomy serum AFP correlated independently and significantly to increased risk with retroperitoneal metastases. In pathological stage I patients, vascular invasion, absence of teratoma, and a short interval between orchiectomy and RPLND indicated an increased risk of relapse. Radiographic examination of the retroperitoneum did not significantly correlate with lymph-node metastases, and postorchiectomy markers were not evaluated." @default.
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- W164582092 date "1994-01-01" @default.
- W164582092 modified "2023-09-27" @default.
- W164582092 title "Surgery in Non-Seminomatous Germ Cell Tumours of the Testis" @default.
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- W164582092 doi "https://doi.org/10.1016/b978-0-08-042198-8.50078-9" @default.
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